SCHEMBL3242722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12749081	0.83	TP53 (0.63)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL5929477	0.83	TP53 (0.52)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL4028646	0.79	TP53 (0.50)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL1071885	0.79	TP53 (0.50)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL2094938	0.78	ALDH1A1 (0.46)	TP53ALOX15MAPTALDH1A1CYP3A4
	SCHEMBL6462571	0.77	TP53 (0.53)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL3242725	0.77	TP53 (0.62)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL15464534	0.77	TP53 (0.49)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL8673129	0.76	TP53 (0.47)	TP53ALOX15KDM4EMAPTALDH1A1
	SCHEMBL9123683	0.76	ELANE (0.49)	TP53ALOX15KDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.