Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653245 | 0.82 | PTGS2 (0.54) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30144760 | 0.79 | PTGS2 (0.52) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30877921 | 0.79 | PTGS2 (0.52) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8705170 | 0.79 | PTGS2 (0.52) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8705175 | 0.79 | PTGS2 (0.52) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8518215 | 0.76 | PTGS2 (0.59) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27874435 | 0.75 | KMT2A (0.46) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8389316 | 0.74 | MAPK14 (0.64) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9806352 | 0.71 | FGF23 (0.41) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6810189 | 0.71 | FGF23 (0.46) | FGF23PTGS2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689291-B1 | MIXTURE OF POLAR COMPOUNDS HAVING POSITIVE DIELECTRIC ANISOTROPY, COMPRISING AT LEAST ONE FLUOROPHENYLCYCLOHEXENE DERIVATIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-02-10 | — | — | US | claimed |
| JP-6306361-A | — | — | None | — | — | JP | disclosed |
| CN-117881668-A | Compound based on isoindoline substituted glutarimide skeleton and application thereof | 标新生物医药科技(上海)有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-1780193-B1 | LIQUID CRYSTAL MATERIAL, METHOD FOR PRODUCING LIQUID CRYSTAL MATERIAL AND LIQUID CRYSTAL DEVICE | JAPAN SCIENCE & TECH AGENCY (JP) | 2010-05-19 | — | — | EP | disclosed |
| JP-2009138204-A | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH | 2009-06-25 | — | — | JP | disclosed |
| JP-2005113152-A | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH | 2005-04-28 | — | — | JP | disclosed |
| US-6689291-B1 | MIXTURE OF POLAR COMPOUNDS HAVING POSITIVE DIELECTRIC ANISOTROPY, COMPRISING AT LEAST ONE FLUOROPHENYLCYCLOHEXENE DERIVATIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-02-10 | — | — | US | disclosed |
| US-6689291-B1 | MIXTURE OF POLAR COMPOUNDS HAVING POSITIVE DIELECTRIC ANISOTROPY, COMPRISING AT LEAST ONE FLUOROPHENYLCYCLOHEXENE DERIVATIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-02-10 | — | — | US | disclosed |
| JP-H06306361-A | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH | 1994-11-01 | — | — | JP | disclosed |