Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3742361 | 0.98 | CYP3A4 (0.41) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10585975 | 0.77 | TAS1R3 (0.39) | SLC6A2SLC6A4SLC6A3ALOX5LMNA | |
| SCHEMBL28638700 | 0.77 | CYP3A4 (0.40) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27302372 | 0.77 | CES2 (0.37) | ALOX5LMNAPOLBCES2CES1 | |
| SCHEMBL27858573 | 0.77 | CES2 (0.37) | ALOX5LMNAPOLBCES2CES1 | |
| SCHEMBL27950901 | 0.73 | TSHR (0.36) | CYP3A4ALOX5LMNACES2CES1 | |
| SCHEMBL7013049 | 0.73 | SLC6A2 (0.44) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6278080 | 0.73 | SLC6A2 (0.51) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28770359 | 0.72 | EPHX1 (0.41) | LMNACES2CES1KEAP1SMN1; SMN2 | |
| SCHEMBL3243865 | 0.72 | ALOX5 (0.45) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541569-B1 | PROCESS FOR PRODUCING N-MONOALKYL-3-HYDROXY-3-(2-THIENYL)PROPANAMINE AND INTERMEDIATE | SUMITOMO SEIKA CHEMICALS (JP) | 2010-05-12 | — | — | EP | disclosed |
| US-7550605-B2 | Process for preparation of an anitdepressant compound | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2009-06-23 | — | — | US | disclosed |
| US-20070191616-A1 | Process for preparation of an antidepressant compound | SUN PHAMACEUUTICAL INDUSTRIES LTD. (IN) | 2007-08-16 | — | — | US | disclosed |
| WO-2006027798-A2 | A PROCESS FOR PREPARATION OF AN ANTIDEPRESSANT COMPOUND | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191616-A1 | Process for preparation of an antidepressant compound | TPH1, TPH2, HTR4 | CYP3A4 114/4885CYP2D6 146/4885SLC6A2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.