Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640115 | 0.86 | AGXT (0.56) | AGXTTDP1NQO1 | |
| SCHEMBL3158699 | 0.80 | TAAR1 (0.60) | WDR5DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL20512950 | 0.79 | CA12 (0.58) | ACHEAGXTALDH1A1TDP1CA1 | |
| Hydrochloric Acid SCHEMBL3522994 | 0.78 | TAAR1 (0.58) | WDR5DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL2470401 | 0.78 | DRD2 (0.59) | WDR5DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL313373 | 0.78 | DRD2 (0.64) | WDR5DRD2DRD4DRD3ACHE | |
| SCHEMBL1688857 | 0.78 | ACHE (0.52) | WDR5DRD2DRD4DRD3ACHE | |
| SCHEMBL13461370 | 0.77 | DRD2 (0.47) | WDR5DRD2DRD4DRD3ACHE | |
| SCHEMBL14159033 | 0.77 | ACHE (0.46) | WDR5DRD2DRD4DRD3ACHE | |
| SCHEMBL6849781 | 0.77 | DRD2 (0.57) | WDR5DRD2DRD4DRD3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399540-A1 | BROMINATED FLAME-RETARDANT TETRAZINES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-12-24 | — | — | US | disclosed |
| US-20150266810-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION | V-BAC HOLDING CORP. (CA) | 2015-09-24 | — | — | US | disclosed |
| US-8895680-B2 | Redox curing-type nonaqueous curable composition | KURARAY NORITAKE DENTAL INC. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20100240798-A1 | REDOX-CURING TYPE NONAQUEOUS CURABLE COMPOSITION | KURARAY MEDICAL INC. (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-1780223-B1 | REDOX CURING-TYPE NONAQUEOUS CURABLE COMPOSITION | KURARAY MEDICAL INC (JP) | 2010-07-28 | — | — | EP | disclosed |
| US-20080081889-A1 | Free radical monomers, organic peroxide and powdered water soluble reducing compound; high adhesive strength against wetting material; teeth and bone restoration | KURARAY MEDICAL INC. (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1780223-A1 | REDOX CURING-TYPE NONAQUEOUS CURABLE COMPOSITION | Kuraray Medical Inc. (JP) | 2007-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266810-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION | TRPC4, TRPC3, TRPC1 | WDR5 1631/4885DRD2 3581/4885DRD4 3092/4885 |
| US-20100240798-A1 | REDOX-CURING TYPE NONAQUEOUS CURABLE COMPOSITION | LPO, CDH1, GPX4 | WDR5 128/4885DRD2 971/4885DRD4 1376/4885 |
| US-20200399540-A1 | BROMINATED FLAME-RETARDANT TETRAZINES | PBRM1, NBAS, TIPRL | WDR5 791/4885DRD2 2813/4885DRD4 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.