⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363048 | 0.80 | KMT2A (0.31) | — | |
| SCHEMBL6151160 | 0.76 | FAAH (0.37) | — | |
| SCHEMBL116713 | 0.72 | — | — | |
| SCHEMBL7346515 | 0.72 | — | — | |
| SCHEMBL8011357 | 0.70 | — | — | |
| SCHEMBL18420497 | 0.70 | THRB (0.31) | — | |
| SCHEMBL16208243 | 0.69 | — | — | |
| SCHEMBL28809706 | 0.67 | MCL1 (0.39) | — | |
| SCHEMBL5263794 | 0.67 | ALDH1A1 (0.34) | — | |
| SCHEMBL2897138 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210584-A1 | Stable polymeric composition comprising an epothilone and an amphiphilic block copolymer | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-07-28 | — | — | EP | disclosed |
| US-20090163450-A1 | COMBINATIONS COMPRISING A PROSTAGLANDIN AND USES THEREOF | BAYER SCHERING PHARMA AG (DE) | 2009-06-25 | — | — | US | disclosed |
| WO-2009074233-A1 | SURFACE-MODIFIED NANOPARTICLES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | disclosed |
| EP-2070521-A1 | Surface-modified nanoparticles | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2009068190-A2 | COMBINATIONS COMPRISING A PROSTAGLANDIN AND USES THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |
| EP-2065054-A1 | Combinations comprising a prostaglandin and uses thereof | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-03 | — | — | EP | disclosed |