Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Abietic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.80 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.80 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.80 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.80 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.80 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.80 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abietic Acid SCHEMBL30065400 | 1.00 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL324776 | 1.00 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL8335225 | 0.99 | HSD17B10 (0.81) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL30176404 | 0.99 | HSD17B10 (0.81) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL8335223 | 0.99 | HSD17B10 (0.81) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL600776 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL5711211 | 0.98 | PDK1 (0.83) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL10524200 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL16401716 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL152817 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060117-A | Poly (itaconate-butadiene-styrene) terpolymer, rubber composite material and preparation method | 北京化工大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122037068-A | Itaconate-ethylene copolymer and preparation method thereof | 北京化工大学 | 2026-05-15 | — | — | CN | claimed |
| CN-120157999-A | Functionalized butyl latex and preparation method thereof, and functionalized butyl latex product and preparation method thereof | 山东京博中聚新材料有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-120158002-A | Ultrahigh-toughness ABS resin and preparation method thereof | 中国石油天然气股份有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-120118446-A | Heat-resistant acrylic ester-styrene-acrylonitrile core-shell grafted copolymer, latex thereof and preparation method thereof | 上海中化科技有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120118447-A | Silicon-containing acrylic ester-styrene-acrylonitrile core-shell graft copolymer, latex thereof and preparation method thereof | 上海中化科技有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120059083-A | ABS resin and preparation method thereof | 万华化学集团股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120005097-A | Chemically modified nitrile rubber and preparation method thereof | 中国石油天然气股份有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119978235-A | Nitrile rubber and preparation method and application thereof | 中国石油天然气股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119978231-A | Preparation method and application of polybutadiene latex emulsion and preparation method of MBS powder | 万华化学集团股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-111019046-A | Preparation method of nitrile rubber | 中国石油天然气股份有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-110982013-A | Preparation method of polybutadiene latex with low gel content and prepared polybutadiene latex | 万华化学集团股份有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110818849-A | Low-odor polymer latex and preparation method thereof | 万华化学集团股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-107306496-B | Rubbery polymer, process for producing the same, graft copolymer, and thermoplastic resin composition | 株式会社LG化学 | 2020-02-21 | — | — | CN | claimed |
| US-7812073-B2 | Preparation method of small particle sized polybutadiene latex used for the production of ABS | CHINA NATIONAL PETROLEUM CORPORATION (CN) | 2010-10-12 | — | — | US | claimed |
| WO-2009133413-A1 | FORMULATION BASED ON MICRONIZED CLINOPTILOLITE AS A THERAPEUTIC AGENT FOR REMOVAL OF TOXINS, BACTERIA AND VIRUSES FROM ORGANISM | NOVATECH D.O.O. (HR) | 2009-11-05 | — | — | WO | claimed |
| US-20090076205-A1 | Preparation method of small particle sized polybutadiene latex used for the production of ABS | CHINA NATIONAL PETROLEUM CORPORATION DAQING PETRO-CHEMICAL COMPLEX (CN) | 2009-03-19 | — | — | US | claimed |
| US-4192767-A | Aqueous surfactant solutions and oil-in-water emulsions | TEXACO INC. (US) | 1980-03-11 | — | — | US | claimed |
| US-4192755-A | Process for recovering hydrocarbons from a hydrocarbon-bearing formation | TEXACO INC. (US) | 1980-03-11 | — | — | US | claimed |
| US-4134415-A | Pipeline transportation of heavy crude oil | TEXACO INC. (US) | 1979-01-16 | — | — | US | claimed |