Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255978 | 0.87 | FEN1 (0.39) | KDM4EGABRA1GABRB2MEN1KMT2A | |
| SCHEMBL3249084 | 0.87 | JAK2 (0.39) | KDM4EGABRA1GABRB2RAB9AGABRP | |
| SCHEMBL3249826 | 0.86 | KDM4E (0.35) | KDM4EGABRA1GABRB2MEN1KMT2A | |
| SCHEMBL3255432 | 0.83 | MET (0.41) | KDM4EMEN1KMT2APOLBCYP2C9 | |
| SCHEMBL3241840 | 0.82 | KDM4E (0.41) | KDM4EGABRA1GABRB2MEN1KMT2A | |
| SCHEMBL3250557 | 0.81 | MAPT (0.41) | KDM4EMEN1KMT2APOLBCYP2C9 | |
| SCHEMBL3249036 | 0.81 | TET2 (0.36) | PARGKDM4EGABRA1GABRB2MEN1 | |
| SCHEMBL3247465 | 0.81 | CRHBP (0.47) | KDM4EMEN1KMT2APOLBCYP2C9 | |
| SCHEMBL3247431 | 0.80 | MAPT (0.48) | KDM4EMEN1KMT2APOLBCYP2C9 | |
| SCHEMBL3248591 | 0.80 | TAS2R14 (0.43) | KDM4EMEN1KMT2APOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |