Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476714 | 0.97 | CES1 (0.41) | CES1CES2TSHRDAONAPRT | |
| Fluoride SCHEMBL9750381 | 0.94 | CES1 (0.39) | CES1CES2TSHRDAONAPRT | |
| Bromide SCHEMBL28303463 | 0.78 | CES1 (0.50) | CES1CES2TSHRDAONAPRT | |
| Bromide SCHEMBL26697305 | 0.78 | CES1 (0.50) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL67982 | 0.75 | CES1 (0.53) | CES1CES2TSHRDAONAPRT | |
| Benzene SCHEMBL28326432 | 0.75 | CES1 (0.53) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL22361301 | 0.72 | ESR1 (0.48) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL26583197 | 0.72 | CES2 (0.44) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL9804411 | 0.72 | CES2 (0.44) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL9580190 | 0.72 | CES1 (0.50) | CES1CES2TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026087965-A1 | COMPOSITION COMPRISING EPOXY RESIN WITH CONSTRAINED AROMATIC RINGS AND PHOTOBASE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-04-30 | — | — | WO | disclosed |
| WO-2025200154-A1 | TWO-PART EPOXY COMPOSITION COMPRISING THIOL CURATIVE, AND CATALYST | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-10-02 | — | — | WO | disclosed |
| US-12306577-B2 | Electrophotographic member and electrophotographic image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2025-05-20 | — | — | US | disclosed |
| US-20240309240-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2024-09-19 | — | — | US | disclosed |
| EP-4079800-B1 | ELECTROPHOTOGRAPHIC MEMBER AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KK (JP) | 2023-12-06 | — | — | EP | disclosed |
| CN-112007622-B | Molecularly imprinted polymer beads for metal extraction and uses thereof | 第六波创新公司 | 2023-01-10 | — | — | CN | disclosed |
| EP-3653663-B1 | MOLDED ARTICLE AND ITS PRODUCTION METHOD | TORAY INDUSTRIES (JP) | 2022-12-28 | — | — | EP | disclosed |
| EP-4079800-A1 | ELECTROPHOTOGRAPHIC MEMBER AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2022-10-26 | — | — | EP | disclosed |
| US-20220334506-A1 | ELECTROPHOTOGRAPHIC MEMBER AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2022-10-20 | — | — | US | disclosed |
| WO-2022210246-A1 | EPOXY RESIN COMPOSITION, CURED EPOXY RESIN PRODUCT, AND COATED FIBER-REINFORCED RESIN MOLDED ARTICLE OBTAINED USING SAME | 東レ株式会社 | 2022-10-06 | — | — | WO | disclosed |
| US-8597579-B1 | Molecularly imprinted polymer-denuder based sensors | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2660196-A1 | MANUFACTURING METHOD FOR FLUOROSULFONYLIMIDE AMMONIUM SALT | Nippon Soda Co., Ltd. (JP) | 2013-11-06 | — | — | EP | disclosed |
| WO-2013030193-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-03-07 | — | — | WO | disclosed |
| EP-2029601-B1 | PYRIDOPYRIMIDINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-06-02 | — | — | EP | disclosed |
| US-7572801-B2 | Pyridopyrimidinone derivatives which are HM74A agonists | HOFFMANN-LA ROCHE INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7416703-B2 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-08-26 | — | — | US | disclosed |
| US-20070275987-A1 | Novel pyridopyprimidinone derivatives which are HM74A agonists | HOFFMAN-LA ROCHE INC | 2007-11-29 | — | — | US | disclosed |
| US-7273953-B2 | Process for producing arylamine | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20060069287-A1 | Process for producing arylamine | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| US-20050019218-A1 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds | MURRAY GEORGE M (US) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069287-A1 | Process for producing arylamine | TYR, AADAC, AOC2 | CES1 2515/4885CES2 393/4885TSHR 605/4885 |
| US-20070275987-A1 | Novel pyridopyprimidinone derivatives which are HM74A agonists | GPR119, HCAR1, GPR84 | CES1 749/4885CES2 3977/4885TSHR 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.