Stearic Acid

Stearic Acid

SCHEMBL324920

C1COCCN1.CCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.61
PPARG P37231 7/20 0.61
PPARD Q03181 7/20 0.61
PPARA Q07869 7/20 0.61
HDAC11 Q96DB2 5/20 0.61
TSHR P16473 4/20 0.61
PTPN1 P18031 3/20 0.61
FABP4 P15090 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TLR2 O60603 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
KMT2A Q03164 2/20 0.61
ALOX15 P16050 2/20 0.61
HSD17B10 Q99714 2/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
SLC22A8 Q8TCC7 1/20 0.61
MEN1 O00255 1/20 0.61
ESR1 P03372 1/20 0.61
PDE4A P27815 1/20 0.61
PDE3A Q14432 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octanoic Acid SCHEMBL7158836 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL21145143 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL323832 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL324684 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Undecanoate SCHEMBL21145180 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Nonanoate SCHEMBL21145100 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL324051 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL11650234 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Hexanoate SCHEMBL21145279 0.98 AKR1B1 (0.59) GPR84PPARGPPARDPPARAHDAC11
Valeric Acid SCHEMBL8526265 0.93 AKR1B1 (0.50) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190099342-A1 COOLING PRODUCT SYMRISE AG (DE) 2019-04-04 US claimed
US-4525502-A AMMONIUM OR AMINE SALT OF CARBOXYLIC ACID AS EMULSIFIER FOR POLYSILOXANES; WATERPROOFING; MASONRY GENERAL ELECTRIC COMPANY (US) 1985-06-25 US claimed
US-4152469-A Method of forming a magnetic recording and storage device having high abrasion resistance CORNING GLASS WORKS (US) 1979-05-01 US claimed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
EP-4732825-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-29 EP disclosed
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS SYMRISE AG (DE) 2026-04-09 US disclosed
EP-4025675-B1 A PERFUME OIL MIXTURE SYMRISE AG (DE) 2026-03-18 EP disclosed
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2026-02-19 US disclosed
US-20260041094-A1 Compositions Comprising an Antimicrobial Boosting Agent SYMRISE AG (DE) 2026-02-12 US disclosed
EP-4687810-A1 PREPARATIONS COMPRISING HYDROXY PINACOLONE RETINOATE Symrise AG (DE) 2026-02-11 EP disclosed
EP-4110276-B1 COMPOSITIONS COMPRISING ALKANEDIOLS SYMRISE AG (DE) 2026-01-28 EP disclosed
US-4634633-A THERMOPLASTIC POLYURETHANE-UREA SONY CORPORATION (JP) 1987-01-06 US disclosed
US-4632878-A ELECTRON BEAM CROSSLINKED POLYESTER URETHANE POLY(METH)ACRYLATE CONTAINING ISOCYANURATE RINGS FUJI PHOTO FILM CO., LTD. (JP) 1986-12-30 US disclosed
EP-0146897-A2 Magnetic recording medium SONY CORPORATION (JP) 1985-07-03 EP disclosed
US-4525502-A AMMONIUM OR AMINE SALT OF CARBOXYLIC ACID AS EMULSIFIER FOR POLYSILOXANES; WATERPROOFING; MASONRY GENERAL ELECTRIC COMPANY (US) 1985-06-25 US disclosed
EP-0143337-A1 Magnetic recording medium SONY CORPORATION (JP) 1985-06-05 EP disclosed
US-4502540-A Tertiary oil recovery MOBIL OIL CORPORATION (US) 1985-03-05 US disclosed
US-4337288-A WITH CONTROLLED SURFACE ROUGHNESS FUJI PHOTO FILM CO., LTD. (JP) 1982-06-29 US disclosed
US-4253886-A Corrosion resistant ferromagnetic metal powders and method of preparing the same FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed
US-3971439-A Designing micellar displacement systems to minimize adsorption MARATHON OIL COMPANY (US) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190099342-A1 COOLING PRODUCT TRPA1, TRPV2, NISCH GPR84 4329/4885PPARG 487/4885PPARD 448/4885
US-20260041094-A1 Compositions Comprising an Antimicrobial Boosting Agent TLR7, MYC, ERG28 GPR84 543/4885PPARG 1774/4885PPARD 3398/4885
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL RBP4, LRAT, RARB GPR84 426/4885PPARG 108/4885PPARD 953/4885
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS PTGS2, PTGES2, PTGS1 GPR84 696/4885PPARG 697/4885PPARD 1742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.