SCHEMBL3250210

SCHEMBL3250210

C=CC(=O)OCCNC(=O)Nc1ccccc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.57
ITGAV P06756 2/20 0.57
KMT2A Q03164 4/20 0.53
MEN1 O00255 2/20 0.53
ITGB1 P05556 1/20 0.52
ITGA5 P08648 1/20 0.52
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
DDX3X O00571 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3243631 0.85 MARS1 (0.44) ITGB3ITGAVKMT2AMEN1ALDH1A1
SCHEMBL22190115 0.84 EPHX1 (0.49) ITGB3ITGAVKMT2AMEN1ALDH1A1
SCHEMBL3251793 0.82 EPHX1 (0.60) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL3252284 0.82 GOT1 (0.48) KMT2AMEN1ALDH1A1MAPTCA12
SCHEMBL3253121 0.82 ITGB3 (0.57) ITGB3ITGAVKMT2AMEN1ITGB1
SCHEMBL5705948 0.81 THRB (0.41) ITGB3ITGAVKMT2AALDH1A1MAPT
SCHEMBL10093588 0.81 EPHX1 (0.46) KMT2AMEN1ALDH1A1MAPTPOLB
SCHEMBL3252507 0.81 NPSR1 (0.53) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL10093587 0.80 THRB (0.43) KMT2AMEN1ALDH1A1MAPTGAA
SCHEMBL3254771 0.79 KCNMA1 (0.46) KMT2AMEN1MAPTGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed