SCHEMBL3250593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20082245	0.93	P2RY14 (0.39)	P2RY14SPRALDH1A1NPC1RAB9A
	SCHEMBL19775106	0.90	HPGD (0.45)	SPRALDH1A1NPC1RAB9AKDM4E
	SCHEMBL3241197	0.89	HPGD (0.44)	SPRALDH1A1NPC1RAB9AKDM4E
	SCHEMBL3249756	0.88	NPC1 (0.50)	ALDH1A1NPC1RAB9AKDM4ECDK4
	SCHEMBL19775298	0.88	STAT3 (0.39)	SPRALDH1A1NPC1RAB9AKDM4E
	SCHEMBL3249088	0.88	HPGD (0.51)	ALDH1A1NPC1RAB9AKDM4EHDAC4
	SCHEMBL19152023	0.88	SPR (0.37)	P2RY14SPRALDH1A1NPC1RAB9A
	SCHEMBL3254638	0.87	SPR (0.41)	SPRALDH1A1NPC1RAB9AKDM4E
	SCHEMBL8104105	0.86	GABRA5 (0.43)	SPRALDH1A1NPC1RAB9AKDM4E
	SCHEMBL3250269	0.86	TRPV1 (0.43)	SPRALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.