SCHEMBL3249756

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3249801	0.96	ALDH1A1 (0.47)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL19775117	0.93	NPC1 (0.49)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL19775106	0.91	HPGD (0.45)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL3241197	0.90	HPGD (0.44)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL8104105	0.89	GABRA5 (0.43)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL19775298	0.89	STAT3 (0.39)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL3249088	0.89	HPGD (0.51)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL3254638	0.88	SPR (0.41)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL3250593	0.88	P2RY14 (0.42)	NPC1RAB9AALDH1A1KDM4EHDAC4
	SCHEMBL11357771	0.88	ALDH1A1 (0.37)	NPC1RAB9AALDH1A1KDM4EHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.