SCHEMBL3241197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19775106	0.99	HPGD (0.45)	HPGDALDH1A1YEATS4MAPK14HDAC4
	SCHEMBL19775142	0.92	YEATS4 (0.46)	HPGDALDH1A1YEATS4MAPK14HDAC4
	SCHEMBL21230299	0.91	YEATS4 (0.45)	HPGDALDH1A1YEATS4MAPK14HDAC4
	SCHEMBL3249801	0.91	ALDH1A1 (0.47)	HPGDALDH1A1YEATS4MAPK14HDAC4
	SCHEMBL3249756	0.90	NPC1 (0.50)	HPGDALDH1A1HDAC4HDAC6HDAC1
	SCHEMBL19775298	0.90	STAT3 (0.39)	HPGDALDH1A1YEATS4HDAC4HDAC6
	SCHEMBL3249088	0.90	HPGD (0.51)	HPGDALDH1A1HDAC4KMT2ANPC1
	SCHEMBL3250593	0.89	P2RY14 (0.42)	HPGDALDH1A1YEATS4MAPK14HDAC4
	SCHEMBL3254638	0.89	SPR (0.41)	HPGDALDH1A1MAPK14HDAC4HDAC6
	SCHEMBL8104105	0.88	GABRA5 (0.43)	HPGDALDH1A1YEATS4MAPK14HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.