SCHEMBL3252175

SCHEMBL3252175

C=CC(=O)OCCNC(=O)Nc1cccc2c(O)cccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 5/20 0.44
EPHX1 P07099 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CDC25B P30305 3/20 0.42
GSK3B P49841 2/20 0.42
CHEK1 O14757 1/20 0.42
DAPK3 O43293 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
NTRK1 P04629 1/20 0.42
RET P07949 1/20 0.42
MET P08581 1/20 0.42
PIM1 P11309 1/20 0.42
FGFR1 P11362 1/20 0.42
PDGFRA P16234 1/20 0.42
LTK P29376 1/20 0.42
GRK5 P34947 1/20 0.42
MAPK8 P45983 1/20 0.42
CSNK1A1 P48729 1/20 0.42
CDK8 P49336 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3251137 0.92 ALDH1A1 (0.45) TRPV1EPHX1ALDH1A1CDC25BGSK3B
SCHEMBL4930932 0.92 EPHX1 (0.41) TRPV1EPHX1ALDH1A1CDC25BGSK3B
SCHEMBL10093588 0.88 EPHX1 (0.46) EPHX1ALDH1A1GSK3BMAPTMEN1
SCHEMBL3251658 0.88 TRPV1 (0.46) TRPV1EPHX1ALDH1A1CDC25BGSK3B
SCHEMBL3243631 0.87 MARS1 (0.44) EPHX1ALDH1A1GAAMAPTMEN1
SCHEMBL3251793 0.86 EPHX1 (0.60) TRPV1EPHX1ALDH1A1GSK3BGAA
SCHEMBL4930941 0.84 RAB9A (0.39) GAAMEN1LMNAKMT2ACA12
SCHEMBL3252322 0.82 TRPV1 (0.46) TRPV1EPHX1ALDH1A1CDC25BGSK3B
SCHEMBL3252282 0.79 MARS1 (0.47) ALDH1A1GAAMAPTLMNAKMT2A
SCHEMBL3250210 0.79 ITGB3 (0.57) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed