Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255449 | 0.89 | TTR (0.43) | HPGDALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL3254619 | 0.86 | ALOX15 (0.44) | HPGDALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL3252380 | 0.85 | CSF1R (0.43) | CSF1RHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL3255436 | 0.84 | GABRA1 (0.45) | IP6K1CSF1RALDH1A1KDM4EGABRA1 | |
| SCHEMBL3255440 | 0.84 | GABRA1 (0.45) | IP6K1CSF1RALDH1A1KDM4EGABRA1 | |
| SCHEMBL3254675 | 0.83 | ALDH1A1 (0.42) | CSF1RHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL3245331 | 0.83 | GABRA1 (0.45) | CSF1RGABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL3249200 | 0.83 | TUBB4A (0.41) | CSF1RHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL3245670 | 0.83 | CSF1R (0.37) | IP6K1CSF1RHPGDALDH1A1KDM4E | |
| SCHEMBL3245727 | 0.82 | GABRA1 (0.50) | CSF1RHPGDALDH1A1LMNAGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |