Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147911 | 0.89 | TRPV1 (0.46) | MAOAMAOBKDRMTNR1BMTNR1A | |
| SCHEMBL3251532 | 0.88 | MAOA (0.46) | MAOAMAOBPDGFRAKITALDH1A1 | |
| SCHEMBL3247108 | 0.80 | MAPT (0.51) | PDGFRAKITKDRMTNR1BMTNR1A | |
| SCHEMBL1147672 | 0.79 | TRPV1 (0.48) | MAOAMAOBMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL3252106 | 0.77 | KCNH2 (0.46) | MAOAMAOBMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL3252103 | 0.73 | KCNH2 (0.38) | MAOAMAOBALDH1A1LMNAKCNH2 | |
| SCHEMBL3256206 | 0.72 | MTNR1B (0.43) | MAOAMAOBMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL3249967 | 0.72 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3251044 | 0.72 | MTNR1B (0.53) | MTNR1BMTNR1AALDH1A1LMNAEGFR | |
| SCHEMBL3251040 | 0.72 | MTNR1B (0.53) | MTNR1BMTNR1AALDH1A1LMNAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001478-B1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-02 | — | — | EP | claimed |