Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 5/20 | 0.49 |
| ▸ | PRKCG | P05129 | 5/20 | 0.49 |
| ▸ | PRKCB | P05771 | 5/20 | 0.49 |
| ▸ | PRKCA | P17252 | 5/20 | 0.49 |
| ▸ | PRKCH | P24723 | 5/20 | 0.49 |
| ▸ | PRKCI | P41743 | 5/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.49 |
| ▸ | PRKACA | P17612 | 2/20 | 0.49 |
| ▸ | PRKACG | P22612 | 2/20 | 0.49 |
| ▸ | PRKACB | P22694 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415921 | 0.84 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL78989 | 0.84 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3959789 | 0.82 | PRKD3 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL927135 | 0.81 | RAB9A (0.54) | KDRCHEK1FLT3NPC1RAB9A | |
| SCHEMBL31615194 | 0.77 | NPC1 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3148480 | 0.77 | NPC1 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3908537 | 0.74 | PRKD3 (0.59) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL6417753 | 0.74 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL2430291 | 0.73 | CHEK1 (0.61) | KDRCHEK1FLT3NPC1RAB9A | |
| SCHEMBL12424814 | 0.71 | KDR (0.54) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285357-A1 | COMPOSITIONS AND METHODS FOR TRANSDIFFERENTIATING CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-09-14 | — | — | US | disclosed |
| EP-4157264-A1 | COMPOSITIONS AND METHODS FOR TRANSDIFFERENTIATING CELLS | The Regents of the University of California (US) | 2023-04-05 | — | — | EP | disclosed |
| EP-2125683-B1 | 3-BENZOFURANYL-4-INDOLYL-MALEIMIDES AS POTENT GSK-3 INHIBITORS FOR NEURODEGENERATIVE DISORDERS | UNIV ILLINOIS (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8207216-B2 | Benzofuran-3-yl(indol-3-yl) maleimides as potent GSK3 inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-06-26 | — | — | US | disclosed |
| US-20100004308-A1 | Benzofuran-3-yl(indol-3-yl) Maleimides as Potent GSK3 Inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS | 2010-01-07 | — | — | US | disclosed |
| EP-2125683-A1 | 3-BENZOFURANYL-4-INDOLYL MALEIMIDES AS POTENT GSK3 INHIBITORS FOR NEUROGENERATIVE DISORDERS | The Board of Trustees of the University of Illinois (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077138-A1 | 3-BENZOFURANYL-4-INDOLYL MALEIMIDES AS POTENT GSK3 INHIBITORS FOR NEUROGENERATIVE DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004308-A1 | Benzofuran-3-yl(indol-3-yl) Maleimides as Potent GSK3 Inhibitors | GSK3B, GSK3A, GSKIP | PRKD3 941/4885PRKCG 1803/4885PRKCB 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.