Sugi Predict

Sugi Predict / Compounds / SCHEMBL3258261

SCHEMBL3258261

SCHEMBL3258261

CCC(N)(CC)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ DGAT1 O75907 1/20 0.36
▸ ARG1 P05089 1/20 0.35
▸ ARG2 P78540 1/20 0.35
▸ POLB P06746 1/20 0.34
▸ TSHR P16473 4/20 0.33
▸ HPGD P15428 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ ATM Q13315 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ KCNN4 O15554 1/20 0.32
▸ MGAM O43451 2/20 0.31
▸ GAA P10253 2/20 0.31
▸ SI P14410 2/20 0.31
▸ MGAM2 Q2M2H8 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1273805 0.97 ALDH1A1 (0.40) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL12156801 0.86 ALDH1A1 (0.41) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL14864686 0.86 ALDH1A1 (0.41) ALDH1A1MEN1CYP1A2THRBKMT2A
Hydrochloric Acid SCHEMBL27835845 0.84 ALDH1A1 (0.39) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL12661979 0.83 ARG1 (0.41) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL27769856 0.83 MEN1 (0.34) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL13201423 0.81 CYP2C19 (0.35) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL12662196 0.80 FDPS (0.43) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL5192036 0.80 SMPD1 (0.43) MEN1KMT2AARG1ARG2ATM
SCHEMBL4957127 0.79 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists DOMAIN THERAPEUTICS (FR) 2026-01-20 — — US disclosed
EP-4038052-B1 PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS DOMAIN THERAPEUTICS (FR) 2024-02-07 — — EP disclosed
CN-110753690-B Pyridine derivatives 豪夫迈·罗氏有限公司 2023-12-05 — — CN disclosed
US-20220378772-A1 PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS DOMAIN THERAPEUTICS (FR) 2022-12-01 — — US disclosed
CN-109843283-B Urea derivatives 第一三共株式会社 2022-08-30 — — CN disclosed
EP-4038052-A2 PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS Domain Therapeutics (FR) 2022-08-10 — — EP disclosed
CN-114555573-A Prostaglandin E2(PGE2)EP4Receptor antagonists 多曼治疗学公司 2022-05-27 — — CN disclosed
US-20220144765-A1 UREA DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-05-12 — — US disclosed
EP-3586838-B1 AMIDE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2021-10-27 — — EP disclosed
US-20210206716-A1 UREA DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-07-08 — — US disclosed
EP-2076499-B1 PYRAZINE-2-CARBOXAMIDE DERIVATIVES AS CB2 RECEPTOR MODULATORS HOFFMANN LA ROCHE (CH) 2010-05-12 — — EP disclosed
US-7691863-B2 Pyrazine-2-carboxamide derivatives as CB2 receptor modulators HOFFMAN-LA ROCHE INC. (US) 2010-04-06 — — US disclosed
US-20100004159-A1 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES GENFIT (FR) 2010-01-07 — — US disclosed
US-20100004159-A1 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES GENFIT (FR) 2010-01-07 — — US disclosed
CN-101522644-A Pyrazine-2-carboxamide derivatives as cb2 receptor modulators HOFFMANN LA ROCHE (CH) 2009-09-02 — — CN disclosed
EP-2076499-A2 PYRAZINE-2-CARBOXAMIDE DERIVATIVES AS CB2 RECEPTOR MODULATORS F.HOFFMANN-LA ROCHE AG (CH) 2009-07-08 — — EP disclosed
US-20080085905-A1 Pyrazine-2-carboxamide derivatives F. HOFFMAN-LA ROCHE AG (CH) 2008-04-10 — — US disclosed
WO-2008040649-A2 PYRAZINE-2-CARBOXAMIDE DERIVATIVES AS CB2 RECEPTOR MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2008-04-10 — — WO disclosed
WO-2008012470-A2 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES GENFIT (FR) 2008-01-31 — — WO disclosed
US-4234736-A FLUOROPHENYL DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 1980-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists PTGER1, PTGER4, PTGER3 ALDH1A1 687/4885MEN1 3795/4885CYP1A2 864/4885
US-20210206716-A1 UREA DERIVATIVE IDO1, IDO2, TPH1 ALDH1A1 439/4885MEN1 4040/4885CYP1A2 225/4885
US-20080085905-A1 Pyrazine-2-carboxamide derivatives CNR2, CNR1, P2RY2 ALDH1A1 2320/4885MEN1 3643/4885CYP1A2 287/4885
US-20100004159-A1 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES IPO5, PPIP5K2, IPO4 ALDH1A1 1025/4885MEN1 3377/4885CYP1A2 45/4885
US-20220378772-A1 PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS PTGER4, PTGER1, PTGER2 ALDH1A1 950/4885MEN1 3666/4885CYP1A2 579/4885
US-20220144765-A1 UREA DERIVATIVE IDO1, IDO2, TPH1 ALDH1A1 439/4885MEN1 4040/4885CYP1A2 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.