Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255951 | 0.78 | ADAMTS4 (0.45) | LMNAMMP1MMP2MMP3MMP7 | |
| SCHEMBL3251733 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDHSD17B10MEN1 | |
| SCHEMBL3258766 | 0.74 | HSD11B1 (0.54) | HTTPIK3CA | |
| SCHEMBL3256778 | 0.73 | P2RY1 (0.49) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3256970 | 0.72 | ALOX12 (0.46) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL6623052 | 0.72 | KMT2A (0.64) | ALDH1A1LMNAMEN1KMT2APKM | |
| SCHEMBL3253214 | 0.71 | AKT1 (0.46) | METAP2 | |
| SCHEMBL3250345 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MMP2MMP9HPGDHSD17B10 | |
| SCHEMBL3256053 | 0.71 | SCN3A (0.46) | ALDH1A1LMNAMMP1MMP2MMP9 | |
| SCHEMBL3257519 | 0.71 | KMO (0.48) | ALDH1A1LMNAMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461325-B1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2010-05-26 | — | — | EP | claimed |