Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | PKM | P14618 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254187 | 0.89 | MMP9 (0.46) | ALDH1A1MEN1KMT2AHSD17B10HPGD | |
| SCHEMBL3256278 | 0.88 | HDAC3 (0.46) | ALDH1A1PKMMEN1KMT2AHSD17B10 | |
| SCHEMBL3256053 | 0.88 | SCN3A (0.46) | ALDH1A1PKMMEN1KMT2AMMP2 | |
| SCHEMBL3256970 | 0.86 | ALOX12 (0.46) | MEN1KMT2AMMP2MMP9 | |
| SCHEMBL3253214 | 0.85 | AKT1 (0.46) | — | |
| SCHEMBL3257519 | 0.84 | KMO (0.48) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL3256778 | 0.84 | P2RY1 (0.49) | MMP2MMP9CA1 | |
| SCHEMBL3255776 | 0.82 | RAB9A (0.43) | — | |
| SCHEMBL3256693 | 0.80 | ACLY (0.40) | MEN1KMT2A | |
| SCHEMBL3253529 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PKMMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461325-B1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2010-05-26 | — | — | EP | claimed |