Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894826 | 0.87 | PLA2G4B (0.46) | HTT | |
| SCHEMBL8660004 | 0.86 | MAPT (0.51) | HTTCA1CA2 | |
| SCHEMBL3184172 | 0.86 | HTT (0.38) | HTT | |
| SCHEMBL8895986 | 0.86 | NPC1 (0.46) | HTTMMP1 | |
| SCHEMBL6547877 | 0.86 | L3MBTL1 (0.51) | HTT | |
| SCHEMBL5690281 | 0.85 | HTT (0.47) | HTT | |
| SCHEMBL8894549 | 0.85 | TP53 (0.47) | HTT | |
| SCHEMBL6549825 | 0.84 | HTT (0.43) | HTTMMP1 | |
| SCHEMBL6547658 | 0.84 | PPARA (0.48) | HTT | |
| SCHEMBL6548648 | 0.84 | L3MBTL1 (0.55) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016383-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOL DERIVATIVES HAVING PESTICIDAL PROPERTIES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-7608631-B2 | 4-(3,3-dihalo-allyloxy) phenol derivatives having pesticidal properties | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-27 | — | — | US | disclosed |
| US-20050288186-A1 | 4-(3,3-dihalo-allyloxy) phenol derivatives having pesticidal properties | SYNGENTA CROP PROTECTION, INC. | 2005-12-29 | — | — | US | disclosed |
| EP-1537077-A2 | 4-(3,3-DIHALO-ALLYLOXY) PHENOL DERIVATIVES HAVING PESTICIDAL PROPERTIES | Syngenta Participations AG (CH) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020445-A2 | 4-(3,3-DIHALO-ALLYLOXY) PHENOL DERIVATIVES HAVING PESTICIDAL PROPERTIES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288186-A1 | 4-(3,3-dihalo-allyloxy) phenol derivatives having pesticidal properties | DDT, SCO2, GSTO1 | HTT 2004/4885HDAC6 1938/4885KDM1A 2013/4885 |
| US-20100016383-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOL DERIVATIVES HAVING PESTICIDAL PROPERTIES | DDT, QSOX1, SCO2 | HTT 2095/4885HDAC6 1550/4885KDM1A 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.