Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261776 | 0.91 | MAPK1 (0.50) | MAPK1NPSR1GRM5RPS6KA3MEN1 | |
| SCHEMBL3264021 | 0.78 | HPGD (0.40) | MEN1KMT2ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL3260006 | 0.76 | CHEK1 (0.56) | MAPK1NPSR1MEN1KMT2ACNR1 | |
| SCHEMBL3260077 | 0.76 | TTK (0.42) | MAPK1NPSR1MEN1KMT2ACNR1 | |
| SCHEMBL12398406 | 0.75 | NFKB1 (0.46) | MAPK1NPSR1KMT2ACNR1CNR2 | |
| SCHEMBL6132076 | 0.73 | MAPK1 (0.80) | MAPK1NPSR1GRM5MAPK14RPS6KA3 | |
| SCHEMBL13495080 | 0.71 | L3MBTL1 (0.55) | MEN1KMT2ACNR1CNR2GPR55 | |
| SCHEMBL13495378 | 0.69 | SMN1; SMN2 (0.52) | NPSR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10355386 | 0.68 | ALDH1A1 (0.44) | MAPK14GCGRMEN1KMT2ACYP1A2 | |
| SCHEMBL3261016 | 0.67 | KDM4E (0.43) | MAPK1MAPK14GCGRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |