Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | DRD4 | P21917 | 7/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794338 | 0.86 | CYP19A1 (0.57) | DRD2DRD4DRD3CYP19A1F2 | |
| SCHEMBL6991388 | 0.81 | LOXL2 (0.49) | DRD2DRD4DRD3F2GRIN1 | |
| SCHEMBL6991892 | 0.81 | LOXL2 (0.55) | — | |
| SCHEMBL6989797 | 0.81 | DRD2 (0.58) | DRD2DRD4DRD3CYP19A1F2 | |
| SCHEMBL6990646 | 0.80 | DRD2 (0.49) | DRD2DRD4DRD3CYP19A1F2 | |
| SCHEMBL7489906 | 0.79 | HRH3 (0.52) | F2ITK | |
| SCHEMBL31739229 | 0.76 | CYP11B1 (0.50) | CCNCCDK8 | |
| SCHEMBL3262489 | 0.76 | RAB9A (0.48) | F2 | |
| SCHEMBL18798850 | 0.75 | LOXL2 (0.53) | F2 | |
| Water SCHEMBL1898776 | 0.73 | CA1 (0.59) | CYP19A1SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011147-A1 | INDOLE COMPOUNDS | THIA MEDICA AS (NO) | 2010-01-28 | — | — | WO | disclosed |