Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991892 | 0.81 | LOXL2 (0.55) | CYP2A6IDO1LOXL2AHR | |
| SCHEMBL3261643 | 0.79 | TBXAS1 (0.42) | F2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3261635 | 0.77 | ALDH1A1 (0.38) | RAB9AF2 | |
| SCHEMBL3261637 | 0.77 | ALDH1A1 (0.38) | RAB9AF2 | |
| SCHEMBL3260101 | 0.76 | DRD2 (0.49) | F2 | |
| SCHEMBL3260257 | 0.75 | F2 (0.39) | RAB9AF2HDAC3HDAC4HDAC1 | |
| SCHEMBL3260256 | 0.75 | F2 (0.39) | RAB9AF2HDAC3HDAC4HDAC1 | |
| SCHEMBL18798850 | 0.75 | LOXL2 (0.53) | RAB9AF2CYP2A6IDO1LOXL2 | |
| 2-Naphthaldehyde SCHEMBL30229844 | 0.73 | RELA (0.58) | RAB9ACYP2A6 | |
| 2-Naphthaldehyde SCHEMBL27347080 | 0.73 | RELA (0.58) | RAB9ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011147-A1 | INDOLE COMPOUNDS | THIA MEDICA AS (NO) | 2010-01-28 | — | — | WO | disclosed |