Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703080 | 0.79 | PTGS2 (0.49) | MMP2MMP9MMP14PTGS2 | |
| SCHEMBL2294329 | 0.76 | PTGS2 (0.44) | ELANEMMP2MMP9MMP14PTGS2 | |
| SCHEMBL7759652 | 0.74 | HTR2A (0.53) | ELANE | |
| SCHEMBL9352386 | 0.73 | ELANE (0.62) | ELANEGPR119PTGS2 | |
| SCHEMBL3235538 | 0.73 | ABCB11 (0.46) | ELANEMMP2MMP9MMP14PTGS2 | |
| SCHEMBL16702992 | 0.73 | CA2 (0.50) | ELANEMMP2MMP9MMP14PTGS2 | |
| SCHEMBL2291204 | 0.72 | PTGS2 (0.40) | MMP2MMP9MMP14PTGS2 | |
| SCHEMBL8958816 | 0.71 | MMP2 (0.50) | ELANEMMP2MMP9MMP14 | |
| SCHEMBL8958823 | 0.71 | MMP2 (0.50) | ELANEMMP2MMP9MMP14 | |
| SCHEMBL3235550 | 0.71 | ELANE (0.44) | ELANEMMP2MMP9MMP14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017498-A1 | METHODS OF SYNTHESIZING N-HYDROXYSUCCINIMIDYL CARBONATES | XENOPORT, INC. (US) | 2010-02-11 | — | — | WO | disclosed |