Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.44 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP14 | P50281 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 7/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499208 | 0.96 | MMP2 (0.47) | MMP2MMP14MMP9ELANETSHR | |
| SCHEMBL8958941 | 0.96 | MMP2 (0.47) | MMP2MMP14MMP9ELANETSHR | |
| SCHEMBL4628639 | 0.96 | MMP2 (0.47) | MMP2MMP14MMP9ELANETSHR | |
| SCHEMBL10775759 | 0.92 | MMP2 (0.57) | MMP2MMP14MMP9ELANETSHR | |
| Hydrochloric Acid SCHEMBL10701272 | 0.91 | MMP2 (0.56) | MMP2MMP14MMP9ELANETSHR | |
| SCHEMBL15602838 | 0.87 | DGKA (0.51) | MMP2MMP14MMP9TSHRTDP1 | |
| SCHEMBL20959757 | 0.87 | DGKA (0.51) | MMP2MMP14MMP9TSHRTDP1 | |
| SCHEMBL8958829 | 0.86 | MMP8 (0.56) | MMP2MMP14MMP9ELANEL3MBTL1 | |
| SCHEMBL8958816 | 0.85 | MMP2 (0.50) | MMP2MMP14MMP9ELANETSHR | |
| SCHEMBL9732667 | 0.83 | STS (0.59) | TSHRSTSLMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202698-B2 | P-sulphophenyl alkyl carbonates and their use as bleaching activators | AKZO NOBEL NV (NL) | 1996-01-24 | — | — | EP | disclosed |
| US-5043089-A | Bleach activators | AKZO N.V. (NL) | 1991-08-27 | — | — | US | disclosed |
| EP-0210674-B1 | P-SULPHOPHENYL CARBONATES AND DETERGENT COMPOSITIONS CONTAINING THEM | AKZO N.V. (NL) | 1990-05-23 | — | — | EP | disclosed |
| EP-0202698-B1 | P-SULPHOPHENYL ALKYL CARBONATES AND THEIR USE AS BLEACHING ACTIVATORS | Akzo Nobel N.V. (NL) | 1989-10-25 | — | — | EP | disclosed |
| US-4686061-A | BLEACHING ACTIVATOR | AKZO NV (NL) | 1987-08-11 | — | — | US | disclosed |
| EP-0210674-A2 | P-sulphophenyl carbonates and detergent compositions containing them | AKZO N.V. (NL) | 1987-02-04 | — | — | EP | disclosed |
| EP-0202698-A1 | P-sulphophenyl alkyl carbonates and their use as bleaching activators | Akzo Nobel N.V. (NL) | 1986-11-26 | — | — | EP | disclosed |