SCHEMBL3262914

SCHEMBL3262914

C=CCc1cc(CC=C)c(N)cc1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 6/20 0.40
GABRB2 P47870 6/20 0.40
CYP1A2 P05177 2/20 0.36
ALOX15 P16050 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CASP7 P55210 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTK2 Q05397 1/20 0.35
POLB P06746 2/20 0.34
CYP3A4 P08684 2/20 0.32
MAPT P10636 2/20 0.32
XDH P47989 1/20 0.32
IMPDH2 P12268 1/20 0.32
MEN1 O00255 1/20 0.32
ALOX5 P09917 1/20 0.32
GAA P10253 1/20 0.32
GABRB1 P18505 1/20 0.32
RXRA P19793 1/20 0.32
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6423969 0.92 GABRA1 (0.41) GABRA1GABRB2CYP1A2ALOX15ALDH1A1
SCHEMBL15772987 0.87 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL21546534 0.81 GAA (0.40) GABRA1GABRB2POLBCYP3A4GAA
SCHEMBL44699 0.80 GABRA1 (0.48) GABRA1GABRB2CYP1A2ALOX15ALDH1A1
SCHEMBL31290769 0.78 GABRA1 (0.41) GABRA1GABRB2CYP1A2ALOX15ALDH1A1
SCHEMBL454406 0.78 GABRA1 (0.41) GABRA1GABRB2CYP1A2ALOX15ALDH1A1
SCHEMBL1772134 0.78 GABRA1 (0.41) GABRA1GABRB2CYP1A2ALDH1A1CASP7
SCHEMBL28789106 0.78 HCAR3 (0.33) GABRA1GABRB2GAA
SCHEMBL5907655 0.77 XDH (0.50) GABRA1GABRB2CYP1A2ALOX15ALDH1A1
Hydrochloric Acid SCHEMBL6307100 0.77 GABRA1 (0.39) GABRA1GABRB2CYP1A2ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220034-B1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2015-12-23 EP claimed
US-8668986-B2 Aromatic aldimines and polyurethane compositions which contain aldimine SIKA TECHNOLOGY AG (CH) 2014-03-11 US claimed
US-20100255314-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-10-07 US claimed
EP-2220034-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE Sika Technology AG (CH) 2010-08-25 EP claimed
WO-2009062985-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-05-22 WO claimed
US-4526905-A Chain extenders ETHYL CORPORATION (US) 1985-07-02 US claimed
CN-103702970-B photoalignment material 罗利克有限公司 2018-10-19 CN disclosed
CN-108178832-A Light alignment materials 罗利克有限公司 2018-06-19 CN disclosed
US-9765235-B2 Photoaligning material ROLIC AG (CH) 2017-09-19 US disclosed
EP-2739601-B1 PHOTOALIGNING MATERIAL ROLIC AG (CH) 2016-03-16 EP disclosed
EP-2220034-B1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2015-12-23 EP disclosed
US-20140162076-A1 PHOTOALIGNING MATERIAL ROLIC AG (CH) 2014-06-12 US disclosed
EP-2739601-A1 PHOTOALIGNING MATERIAL Rolic AG (CH) 2014-06-11 EP disclosed
US-20100255314-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-10-07 US disclosed
EP-0484572-B1 Aromatic diamines ALBEMARLE CORP (US) 1995-07-05 EP disclosed
EP-0484572-A1 Aromatic diamines ALBEMARLE CORPORATION (US) 1992-05-13 EP disclosed
US-5064927-A ROOM TEMPERATURE COATINGS; REACTION INJECTION MOLDING POLYMERS ETHYL CORPORATION (US) 1991-11-12 US disclosed
US-5037995-A Aromatic diamine mixtures ETHYL CORPORATION (US) 1991-08-06 US disclosed
US-4973760-A Aromatic diamines ETHYL CORPORATION (US) 1990-11-27 US disclosed
US-4526905-A Chain extenders ETHYL CORPORATION (US) 1985-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100255314-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE ODC1, DDC, SRM GABRA1 1857/4885GABRB2 1427/4885CYP1A2 2493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.