Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495274 | 0.88 | HPGD (0.35) | IKBKBCHUKSMN1; SMN2HPGDLRRK2 | |
| SCHEMBL3264021 | 0.88 | HPGD (0.40) | IKBKBSMN1; SMN2HPGDRAB9ALRRK2 | |
| SCHEMBL3264005 | 0.72 | SMN1; SMN2 (0.38) | IKBKBCHUKHTTSMN1; SMN2HPGD | |
| SCHEMBL3260006 | 0.69 | CHEK1 (0.56) | CHUKHTTSMN1; SMN2HPGDNPC1 | |
| SCHEMBL3261776 | 0.69 | MAPK1 (0.50) | SMN1; SMN2HPGDNPC1RAB9ALRRK2 | |
| SCHEMBL15657239 | 0.68 | PDPK1 (0.53) | CNR1CNR2 | |
| SCHEMBL16661324 | 0.68 | DGAT1 (0.47) | HTTSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL12398406 | 0.68 | NFKB1 (0.46) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL3390203 | 0.66 | MAPK1 (0.43) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6610130 | 0.65 | NQO1 (0.64) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |