Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263304 | 0.88 | IKBKB (0.41) | HPGDKDM4EALDH1A1IKBKBTDP1 | |
| SCHEMBL13495274 | 0.85 | HPGD (0.35) | HPGDKDM4EALDH1A1IKBKBTDP1 | |
| SCHEMBL3390203 | 0.78 | MAPK1 (0.43) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3261016 | 0.70 | KDM4E (0.43) | HPGDKDM4EALDH1A1APOBEC3GTDP1 | |
| SCHEMBL10355386 | 0.68 | ALDH1A1 (0.44) | HPGDKDM4EALDH1A1TDP1LMNA | |
| SCHEMBL3260006 | 0.67 | CHEK1 (0.56) | HPGDKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL3261776 | 0.67 | MAPK1 (0.50) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL12398406 | 0.66 | NFKB1 (0.46) | HPGDKDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL24962583 | 0.64 | IKBKB (0.64) | HPGDKDM4EALDH1A1IKBKBMAP3K14 | |
| SCHEMBL13756271 | 0.63 | NQO1 (0.64) | HPGDKDM4EALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |