Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385375 | 0.92 | RAB9A (0.45) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3261292 | 0.86 | ALDH1A1 (0.46) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3393032 | 0.85 | ATM (0.46) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3264381 | 0.81 | TRPM8 (0.43) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3260654 | 0.79 | MAPT (0.50) | NPSR1BRAFALDH1A1KDM4EMAPT | |
| SCHEMBL3264346 | 0.76 | KDM4E (0.43) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3261663 | 0.76 | NPSR1 (0.45) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3260789 | 0.76 | NPSR1 (0.45) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3391830 | 0.74 | DHODH (0.38) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13495117 | 0.74 | DHODH (0.38) | NPSR1ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |