SCHEMBL3265665

SCHEMBL3265665

O=C(O)Oc1cnn2c(O)c(-c3c(Cl)cncc3Cl)c(O)nc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13232454 0.77 ALDH1A1 (0.44)
SCHEMBL3258125 0.67 ALDH1A1 (0.38)
SCHEMBL9320822 0.62 GAA (0.41)
SCHEMBL4970754 0.58 KDM4E (0.35)
SCHEMBL11077641 0.57 MMP1 (0.35)
SCHEMBL4969892 0.55 EPHB3 (0.43)
SCHEMBL4968654 0.55 POLB (0.37)
SCHEMBL9329411 0.54 HCAR2 (0.37)
SCHEMBL7047960 0.54 AKR1C4 (0.37)
SCHEMBL28440693 0.54 AKR1C2 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2158204-A2 HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYL CARBOXYLIC ACID DERIVATIVES Bayer CropScience AG (DE) 2010-03-03 EP disclosed
WO-2008151735-A2 HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYL CARBOXYLIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2008-12-18 WO disclosed