Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.47 |
| ▸ | HTR3B | O95264 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414387 | 0.79 | PBRM1 (0.62) | RAB9ANPC1POLBALDH1A1KMT2A | |
| SCHEMBL4215371 | 0.79 | PBRM1 (0.62) | RAB9ANPC1POLBALDH1A1KMT2A | |
| SCHEMBL3942488 | 0.76 | RAB9A (0.49) | RAB9ANPC1POLBSMN1; SMN2KMT2A | |
| SCHEMBL26259075 | 0.75 | ALDH1A1 (0.57) | RAB9ANPC1ALDH1A1KMT2APBRM1 | |
| SCHEMBL2079279 | 0.74 | HTR3E (0.76) | RAB9ANPC1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4954977 | 0.73 | GPR84 (0.77) | RAB9ANPC1POLBALDH1A1LMNA | |
| SCHEMBL3262320 | 0.72 | RAB9A (0.47) | RAB9ANPC1POLBSMN1; SMN2KMT2A | |
| SCHEMBL3119512 | 0.72 | RAB9A (0.53) | RAB9ANPC1POLBSMN1; SMN2KMT2A | |
| SCHEMBL3118257 | 0.72 | ADAM17 (0.54) | RAB9ANPC1ALDH1A1KMT2APBRM1 | |
| SCHEMBL2078783 | 0.72 | HTR3E (0.78) | RAB9ANPC1POLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |