Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665545 | 0.84 | HTR6 (0.49) | BPTFDRD2HTR6NR1H2NR1H3 | |
| SCHEMBL32665449 | 0.81 | BPTF (0.51) | BPTFHTR6CHRM4TPSAB1HTR1A | |
| SCHEMBL32665512 | 0.81 | NR1H2 (0.39) | BPTFDRD2HTR6NR1H2NR1H3 | |
| SCHEMBL32665470 | 0.76 | HTR6 (0.40) | DRD2HTR6NR1H2NR1H3GPR119 | |
| SCHEMBL32665139 | 0.74 | GPR119 (0.52) | DRD2NR1H2NR1H3GPR119 | |
| SCHEMBL718248 | 0.73 | BPTF (0.53) | BPTF | |
| SCHEMBL8124584 | 0.72 | ADRB1 (0.56) | BPTFDRD2CHRM4CYP3A4HTR1A | |
| SCHEMBL31726402 | 0.72 | HTR6 (0.45) | BPTFDRD2HTR6GPR119CHRM4 | |
| SCHEMBL6507154 | 0.71 | DRD2 (0.59) | BPTFDRD2CHRM4 | |
| SCHEMBL16966426 | 0.71 | CA1 (0.48) | DRD2HTR6NR1H2NR1H3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | BPTF 2276/4885DRD2 4539/4885HTR6 4206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.