Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | DKK1 | O94907 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665624 | 0.85 | VCP (0.42) | BPTFMAPTNOTUMHTR6GUSB | |
| SCHEMBL32665273 | 0.83 | NOTUM (0.38) | BPTFMAPTNOTUMGUSBALDH1A1 | |
| SCHEMBL32665195 | 0.82 | HRH1 (0.37) | BPTFMAPTTPSAB1NOTUMFFAR4 | |
| SCHEMBL32665631 | 0.81 | BPTF (0.53) | BPTFTPSAB1CHRM4HTR1AHTR2A | |
| SCHEMBL32665255 | 0.80 | NOTUM (0.43) | BPTFNOTUMHTR1AHTR6ALDH1A1 | |
| SCHEMBL32665250 | 0.80 | NOTUM (0.43) | BPTFNOTUMHTR1AHTR6ALDH1A1 | |
| SCHEMBL32665021 | 0.80 | HTR1A (0.38) | NOTUMCHRM4CHRM2CHRM1HTR1A | |
| SCHEMBL8124584 | 0.79 | ADRB1 (0.56) | BPTFMAPTFFAR4CHRM4ADRA1D | |
| SCHEMBL32665285 | 0.77 | ALDH1A1 (0.36) | MAPTNOTUMHTR7GUSBALDH1A1 | |
| SCHEMBL32665450 | 0.73 | NOTUM (0.40) | BPTFNOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | BPTF 2276/4885MAPT 4709/4885TPSAB1 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.