Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220898 | 0.91 | MTNR1B (0.39) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL3233902 | 0.88 | RORC (0.39) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL3267163 | 0.86 | EPHX2 (0.37) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL3267545 | 0.86 | ALDH1A1 (0.43) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL690229 | 0.85 | EPHX2 (0.43) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL3228839 | 0.85 | EPHX2 (0.43) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL689276 | 0.85 | EPHX2 (0.43) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL3265553 | 0.83 | HRH2 (0.42) | RORCDHODHALDH1A1MEN1KMT2A | |
| SCHEMBL27856261 | 0.82 | MEN1 (0.44) | MTNR1BRORCDHODHALDH1A1MEN1 | |
| SCHEMBL3232200 | 0.81 | FAAH (0.34) | MTNR1BRORCDHODHALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |