SCHEMBL3267933

SCHEMBL3267933

Cc1ccc(S(=O)(=O)OS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
VDR P11473 1/20 0.53
GAA P10253 4/20 0.50
CA12 O43570 4/20 0.50
CA9 Q16790 4/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
C5AR1 P21730 1/20 0.50
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6490 0.91 GAA (0.59) HTTSMN1; SMN2VDRGAACA12
SCHEMBL64190 0.90 VDR (0.49) HTTSMN1; SMN2VDRGAACA12
SCHEMBL3144536 0.90 VDR (0.49) HTTSMN1; SMN2VDRGAACA12
SCHEMBL2955938 0.90 VDR (0.49) HTTSMN1; SMN2VDRGAACA12
SCHEMBL2962485 0.90 VDR (0.49) HTTSMN1; SMN2VDRGAACA12
SCHEMBL2964106 0.90 VDR (0.49) HTTSMN1; SMN2VDRGAACA12
Water SCHEMBL3352692 0.89 GAA (0.56) HTTSMN1; SMN2VDRGAACA12
SCHEMBL30862469 0.89 GAA (0.56) HTTSMN1; SMN2VDRGAACA12
SCHEMBL64622 0.88 VDR (0.47) HTTSMN1; SMN2VDRGAACA12
SCHEMBL3839712 0.88 VDR (0.47) HTTSMN1; SMN2VDRGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11951103-B2 Pharmaceutical composition KYOWA KIRIN CO., LTD. (JP) 2024-04-09 US claimed
CN-115551505-A Treatment of viral infections, diseases or conditions using selective S1R agonists 普瑞尼亚神经治疗有限公司 2022-12-30 CN claimed
CN-117964442-A Method for preparing polysubstituted alkylaromatic hydrocarbon, polysubstituted alkylaromatic hydrocarbon prepared by the method and application thereof 中国石油化工股份有限公司 2024-05-03 CN disclosed
CN-107615168-B Radiation-sensitive composition 日产化学工业株式会社 2023-12-19 CN disclosed
CN-117215155-A Resist underlayer film material, pattern forming method, and resist underlayer film forming method 信越化学工业株式会社 2023-12-12 CN disclosed
CN-110914241-B Propionic acid derivatives and methods of use thereof 阿维亚拉药品有限公司 2023-11-14 CN disclosed
CN-117008420-A Radiation-sensitive composition 日产化学工业株式会社 2023-11-07 CN disclosed
US-11806343-B2 Inhibitors of DUX4 induction for regulation of muscle function SONIC MASTER LIMITED (VG) 2023-11-07 US disclosed
US-11676814-B2 Material for forming organic film, substrate for manufacturing semiconductor apparatus, method for forming organic film, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-13 US disclosed
CN-115551505-A Treatment of viral infections, diseases or conditions using selective S1R agonists 普瑞尼亚神经治疗有限公司 2022-12-30 CN disclosed
CN-115368412-A Method for preparing minodronic acid 扬子江药业集团北京海燕药业有限公司 2022-11-22 CN disclosed
US-6797731-B2 USE AS SKIN LIGHTENING AGENTS PFIZER INC. 2004-09-28 US disclosed
US-20030190298-A1 Resorcinol derivatives BRADLEY STUART E (GB) 2003-10-09 US disclosed
EP-1037586-A1 UTILIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES FOR DYING FIBERS CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2000-09-27 EP disclosed
WO-1999018916-A2 UTILIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES FOR DYING FIBERS CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-04-22 WO disclosed
EP-0882024-A1 RETROVIRAL PROTEASE INHIBITING COMPOUNDS Abbott Laboratories (US) 1998-12-09 EP disclosed
WO-1997021685-A1 RETROVIRAL PROTEASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1997-06-19 WO disclosed
US-4281176-A ESTERIFICATION OF ETHYLENE WITH A CARBOXYLIC ACID IN THE PRESENCE OF AN ACID CATALYST RHONE-POULENC INDUSTRIES (FR) 1981-07-28 US disclosed
US-4242510-A Cephalosporin compounds and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed
US-4118571-A ANTIALLERGENS STERLING DRUG INC. (US) 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11806343-B2 Inhibitors of DUX4 induction for regulation of muscle function MUSK, MERTK, PRKDC HTT 4149/4885SMN1; SMN2 907/4885VDR 1754/4885
US-20030190298-A1 Resorcinol derivatives LRAT, NQO1, ALDH1A2 HTT 3453/4885SMN1; SMN2 4867/4885VDR 116/4885
US-11951103-B2 Pharmaceutical composition EGFR, VEGFA, KDR HTT 725/4885SMN1; SMN2 3118/4885VDR 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.