SCHEMBL3267983

SCHEMBL3267983

C=C(C)c1cccc(CN(C)C(=O)OC(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
HSD17B2 P37059 4/20 0.40
HSD17B1 P14061 3/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
ABHD6 Q9BV23 2/20 0.38
HDAC1 Q13547 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
BRD4 O60885 1/20 0.37
BRD3 Q15059 1/20 0.37
TSHR P16473 1/20 0.37
HPGD P15428 1/20 0.37
AOC3 Q16853 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2969425 0.78 CHRNB2 (0.60) MEN1KMT2ACHRNB2CHRNB4CHRNA3
SCHEMBL610124 0.75 NOS1 (0.51) MEN1KMT2AHSD17B2HSD17B1CHRNB2
SCHEMBL820795 0.72 NPC1 (0.55) MEN1KMT2A
SCHEMBL20794226 0.71 MEP1B (0.54) MEN1KMT2AABHD6AOC3
SCHEMBL610694 0.70 BCHE (0.47) HDAC6AOC3
SCHEMBL13135982 0.70 GLS (0.46) MGLLMEN1KMT2AHSD17B2HSD17B1
SCHEMBL10127404 0.70 MMP13 (0.51) MGLLMEN1KMT2ACHRNB2CHRNB4
SCHEMBL29793637 0.69 KMT2A (0.55) MEN1KMT2AHSD17B2HSD17B1CHRNB2
SCHEMBL609257 0.69 KMT2A (0.37) MEN1KMT2AHSD17B2HSD17B1BRD4
SCHEMBL13093377 0.69 CYP4F2 (0.58) KMT2ACHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100038046-A1 USE OF AN AQUEOUS SUSPENSION AND/OR DISPERSION OF MINERAL MATERIALS CONTAINING A HYDROPHOBIC GROUP WATER-SOLUBLE COPOLYMER FOR MAKING A PAPER SHEET COATEX S.A.S. (FR) 2010-02-18 US claimed
EP-1270617-B1 Acrylic copolymer partially or fully soluble in water, cured or not and its use COATEX SAS (FR) 2008-10-22 EP claimed
EP-0892020-B1 Use of a copolymer having surfactant structures as dispersing agent and/or grinding aid COATEX SAS (FR) 2006-07-12 EP claimed
US-20050288428-A1 Water soluble retention agent COATEX S.A. (FR) 2005-12-29 US claimed
EP-0577526-B1 Acrylic copolymer partially or fully soluble in water, cured or not and its use COATEX SAS (FR) 2002-11-20 EP claimed
US-6093764-A DISPERSING MINERAL IN AN AQUEOUS MEDIA CONTAINING WATER, AND A COPOLYMER OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACID, ETHYLENICALLY UNSATURATED MONOMER WITH PHOSPHONIC OR SULFONICGROUPS AND ETHYLENICALLY UNSATURATED OXYALKYLATED COATEX S.A. (FR) 2000-07-25 US claimed
EP-0892111-A1 Aqueous suspensions from mineral materials and their uses PLUESS STAUFER AG (CH) 1999-01-20 EP claimed
EP-0826769-A1 Compatible agent with surfactants used in detergent composition or in cosmetics COATEX S.A. (FR) 1998-03-04 EP claimed
EP-0577525-B1 Stable aqueous zeolite suspensions, their fabrication process and use COATEX SA (FR) 1996-02-21 EP claimed
EP-0577526-A1 Acrylic copolymer partially or fully soluble in water, cured or not and its use COATEX S.A. (FR) 1994-01-05 EP claimed
EP-0577525-A1 Stable aqueous zeolite suspensions, their fabrication process and use COATEX S.A. (FR) 1994-01-05 EP claimed
US-8221587-B2 Use of an aqueous suspension and/or dispersion of mineral materials containing a hydrophobic group water-soluble copolymer for making a paper sheet COATEX S.A.S. (FR) 2012-07-17 US disclosed
US-20100038046-A1 USE OF AN AQUEOUS SUSPENSION AND/OR DISPERSION OF MINERAL MATERIALS CONTAINING A HYDROPHOBIC GROUP WATER-SOLUBLE COPOLYMER FOR MAKING A PAPER SHEET COATEX S.A.S. (FR) 2010-02-18 US disclosed
EP-1997838-A2 Acrylic copolymer partially or fully water-soluble, cross-linked or not and use thereof COATEX S.A.S. (FR) 2008-12-03 EP disclosed
EP-1270617-B1 Acrylic copolymer partially or fully soluble in water, cured or not and its use COATEX SAS (FR) 2008-10-22 EP disclosed
EP-0892020-A1 Use of a copolymer having surfactant structures as dispersing agent and/or grinding aid COATEX S.A. (FR) 1999-01-20 EP disclosed
EP-0826769-A1 Compatible agent with surfactants used in detergent composition or in cosmetics COATEX S.A. (FR) 1998-03-04 EP disclosed
EP-0577525-B1 Stable aqueous zeolite suspensions, their fabrication process and use COATEX SA (FR) 1996-02-21 EP disclosed
EP-0577526-A1 Acrylic copolymer partially or fully soluble in water, cured or not and its use COATEX S.A. (FR) 1994-01-05 EP disclosed
EP-0577525-A1 Stable aqueous zeolite suspensions, their fabrication process and use COATEX S.A. (FR) 1994-01-05 EP disclosed