Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 11/20 | 0.69 |
| ▸ | HTR1A | P08908 | 9/20 | 0.69 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577989 | 0.82 | HTR7 (1.00) | HTR7HTR1AHTR6HTR2CADRB1 | |
| SCHEMBL3274862 | 0.81 | HTR7 (0.63) | HTR7HTR1AHTR6HTR2CADRB1 | |
| SCHEMBL6650883 | 0.81 | HTR7 (0.59) | HTR7HTR1AHTR6HTR2CADRB1 | |
| SCHEMBL3269200 | 0.81 | FAAH (0.52) | HTR7HTR1A | |
| SCHEMBL315894 | 0.80 | HTR7 (0.68) | HTR7HTR1AHTR6HTR2CADRB1 | |
| Bromide SCHEMBL6774182 | 0.78 | HTR7 (0.66) | HTR7HTR1AHTR6HTR2CADRB1 | |
| Hydrochloric Acid SCHEMBL11556656 | 0.78 | HTR7 (0.66) | HTR7HTR1AHTR6HTR2CADRB1 | |
| Hydrochloric Acid SCHEMBL9743614 | 0.78 | HTR7 (0.66) | HTR7HTR1AHTR6HTR2CADRB1 | |
| SCHEMBL27580439 | 0.78 | HTR7 (0.55) | HTR7HTR1AHTR6HTR2CADRB1 | |
| Bromide SCHEMBL27376788 | 0.77 | HTR7 (0.64) | HTR7HTR1AHTR6HTR2CADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2199282-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20090163508-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | HTR7 1437/4885HTR1A 1025/4885HTR6 1160/4885 |
| US-20090163508-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | HTR7 1437/4885HTR1A 1025/4885HTR6 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.