Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.68 |
| ▸ | HTR1A | P08908 | 5/20 | 0.68 |
| ▸ | HTR6 | P50406 | 5/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.62 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.62 |
| ▸ | HTR3B | O95264 | 4/20 | 0.62 |
| ▸ | HTR3A | P46098 | 4/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | HTR2C | P28335 | 4/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11556656 | 0.98 | HTR7 (0.66) | HTR7HTR1AHTR6ADRB1HTR3E | |
| Bromide SCHEMBL6774182 | 0.98 | HTR7 (0.66) | HTR7HTR1AHTR6ADRB1HTR3E | |
| Hydrochloric Acid SCHEMBL9743614 | 0.98 | HTR7 (0.66) | HTR7HTR1AHTR6ADRB1HTR3E | |
| Bromide SCHEMBL27376788 | 0.96 | HTR7 (0.64) | HTR7HTR1AHTR6ADRB1HTR3E | |
| Hydrochloric Acid SCHEMBL12817391 | 0.92 | HTR1A (0.59) | HTR7HTR1AHTR6ADRB1HTR3E | |
| SCHEMBL20699709 | 0.86 | BPTF (0.54) | HTR7HTR1AHTTALDH1A1MAPT | |
| SCHEMBL10373948 | 0.86 | BPTF (0.54) | HTR7HTR1AHTTALDH1A1MAPT | |
| SCHEMBL4913199 | 0.83 | HTR7 (0.66) | HTR7HTR1AHTR6ADRB1HTR3E | |
| SCHEMBL30167608 | 0.82 | ALDH1A1 (0.52) | HTR7HTR1ATP53HTTALDH1A1 | |
| SCHEMBL30407553 | 0.82 | BPTF (0.51) | HTR7HTR1ATP53HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661750-B | Ketene-bridged quinazolinone thiazole compound and preparation method and application thereof | 西南大学 | 2022-10-21 | — | — | CN | claimed |
| CN-111944539-B | Fluropiperazine-based benzoxazole liquid crystal compound and preparation method thereof | 西安瑞联新材料股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-111944539-A | Fluropiperazine-based benzoxazole liquid crystal compound and preparation method thereof | 西安瑞联新材料股份有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-104583217-B | Substituted thiophene-fused and furan-fused oxazolopyrimidine-5- (6H) -one compounds | 达特神经科学(开曼)有限公司 | 2017-11-17 | — | — | CN | claimed |
| EP-2861605-B1 | 6-Benzyl-6H-thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-one derivatives as phosphodiesterase-1 (PDE-1) inhibitors for the treatment of e.g. neurological, cognitive and cardiovascular disorders | DART NEUROSCIENCE (CAYMAN) LTD (KY) | 2017-05-03 | — | — | EP | claimed |
| US-9499562-B2 | Substituted thiophene- and furan-fused azolopyrimidine-5-(6H)-one compounds | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2016-11-22 | — | — | US | claimed |
| CN-104046246-B | The chemical-mechanical planarization of tungsten-containing substrate | 气体产品与化学公司 | 2016-06-15 | — | — | CN | claimed |
| US-20160031901-A1 | SUBSTITUTED THIOPHENE- AND FURAN-FUSED AZOLOPYRIMIDINE-5-(6H)-ONE COMPOUNDS | DART NEUROSCIENCE LLC | 2016-02-04 | — | — | US | claimed |
| CN-104583217-A | Substituted thiophene-fused and furan-fused oxazolopyrimidine-5- (6H) -one compounds | DART NEUROSCIENCE CAYMAN LTD | 2015-04-29 | — | — | CN | claimed |
| EP-2861605-A1 | SUBSTITUTED THIOPHENE- AND FURAN-FUSED AZOLOPYRIMIDINE-5-(6H)-ONE COMPOUNDS | Dart Neuroscience (Cayman) Ltd (KY) | 2015-04-22 | — | — | EP | claimed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | claimed |
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | claimed |
| WO-2013192225-A1 | SUBSTITUTED THIOPHENE- AND FURAN-FUSED AZOLOPYRIMIDINE-5-(6H)-ONE COMPOUNDS | DART NEUROSCIENCE (CAYMAN) LTD (KY) | 2013-12-27 | — | — | WO | claimed |
| CN-102924441-A | N-(4-(4-(3-fluorophenyl)piperazin-1-yl)pyrimidin-2-yl)-amide or salts thereof, preparation method and applications | UNIV SOUTH CHINA TECH | 2013-02-13 | — | — | CN | claimed |
| EP-2006271-A9 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2009-07-29 | — | — | EP | claimed |
| EP-2051978-A2 | ACETAMIDE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-04-29 | — | — | EP | claimed |
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | claimed |
| EP-2006271-A2 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2008-12-24 | — | — | EP | claimed |
| WO-2007136875-A2 | ACETAMIDE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| EP-0539180-A1 | Antiviral agents | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-04-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | LTB4R2, LTC4S, LTB4R | HTR7 784/4885HTR1A 478/4885HTR6 1450/4885 |
| US-20160031901-A1 | SUBSTITUTED THIOPHENE- AND FURAN-FUSED AZOLOPYRIMIDINE-5-(6H)-ONE COMPOUNDS | TPMT, PSEN2, GRIN2C | HTR7 286/4885HTR1A 179/4885HTR6 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.