Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.73 |
| ▸ | DRD2 | P14416 | 4/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620729 | 0.92 | HTR1A (0.63) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL31561714 | 0.89 | HTR1A (0.69) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL3159332 | 0.89 | HTR1A (0.69) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL5660418 | 0.89 | HTR1A (0.59) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL10683333 | 0.88 | HTR1A (0.67) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL27481988 | 0.86 | HTR1A (0.56) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL29048659 | 0.86 | HTR1A (0.56) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL21670571 | 0.85 | L3MBTL1 (0.67) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL17197391 | 0.85 | HTR1A (0.79) | HTR1ADRD2ABCB1LMNAPTGER1 | |
| SCHEMBL4183309 | 0.85 | HTR1A (1.00) | HTR1ADRD2ABCB1PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646246-A | Process for synthesizing Levobetaxolol hydrochloride | 青岛首泰农业科技有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-103965041-A | Method for preparing 2-(4-benzyloxy phenyl)ethanol fatty acid ester | HAISO TECHNOLOGY CO LTD | 2014-08-06 | — | — | CN | claimed |
| CN-100532355-C | Technique for synthesizing levorotatory betaxolol hydrochloride | UNIV ZHENGZHOU (CN) | 2009-08-26 | — | — | CN | claimed |
| CN-101085742-A | Technique for synthesizing levorotatory betaxolol hydrochloride | UNIV ZHENGZHOU (CN) | 2007-12-12 | — | — | CN | claimed |
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| US-11365192-B2 | Pyridine compound substituted with azole | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-06-21 | — | — | US | disclosed |
| US-11365192-B2 | Pyridine compound substituted with azole | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-06-21 | — | — | US | disclosed |
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |
| US-11192907-B2 | Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same | QUANTUM GENOMICS (FR) | 2021-12-07 | — | — | US | disclosed |
| US-20210309678-A1 | AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Institut National de la Santé et de la Recherche Médicale (FR) | 2021-10-07 | — | — | US | disclosed |
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20210122741-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2021-04-29 | — | — | US | disclosed |
| WO-1995011226-A1 | SUBSTITUTED BENZENE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND BIOCIDAL COMPOSITION FOR CONTROL OF HARMFUL ORGANISMS CONTAINING THEM | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-04-27 | — | — | WO | disclosed |
| US-5232628-A | Nonionic and anionic surfactante as textile additives, wetting or padding agents | CIBA-GEIGY CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-5126474-A | POLYADDUCTS OF ALKYLENE OXIDE AND STYRENE OXIDE WITH ARYL ALKANOLS | CIBA-GEIGY CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0307106-B1 | P- OR M-TERT BUTOXYPHENETHYL ALCOHOL AND PROCESS FOR PREPARING THE SAME | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0355754-A2 | 2-Benzyloxybenzaldehyde dialkyl acetals, their preparation and use | BASF Aktiengesellschaft (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0307106-A1 | P- or m-tert butoxyphenethyl alcohol and process for preparing the same | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1989-03-15 | — | — | EP | disclosed |
| US-4761420-A | CARDIOVASCULAR DISORDERS | LABORATOIRES SYNTEX S.A. (FR) | 1988-08-02 | — | — | US | disclosed |
| EP-0249245-A2 | Antihypertensive dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1987-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122741-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | CYP2C19, CYP4A11, CYP11B1 | HTR1A 1460/4885DRD2 3279/4885ABCB1 960/4885 |
| US-11192907-B2 | Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same | ANPEP, DNPEP, ENPEP | HTR1A 2938/4885DRD2 4884/4885ABCB1 1136/4885 |
| US-11365192-B2 | Pyridine compound substituted with azole | CYP2C19, CYP4A11, CYP11B1 | HTR1A 1460/4885DRD2 3279/4885ABCB1 960/4885 |
| US-20210309678-A1 | AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | ANPEP, DNPEP, ENPEP | HTR1A 2938/4885DRD2 4884/4885ABCB1 1136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.