Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.50 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.50 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688239 | 0.89 | PLOD2 (0.53) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL32688293 | 0.88 | PLOD2 (0.65) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL32688378 | 0.88 | ALDH1A1 (0.55) | PLOD2PLOD3PLOD1NPC1PKM | |
| SCHEMBL32688300 | 0.86 | ALDH1A1 (0.54) | PLOD2PLOD3PLOD1NPC1ALDH1A1 | |
| SCHEMBL32688003 | 0.85 | GPR119 (0.52) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL21858310 | 0.78 | KDM4E (0.53) | NPC1PKMALDH1A1MAPTMAPK1 | |
| SCHEMBL2322269 | 0.78 | MAPT (0.54) | NPC1PKMALDH1A1MAPTMAPK1 | |
| SCHEMBL13702307 | 0.78 | NPC1 (0.55) | NPC1PKMALDH1A1MAPTMAPK1 | |
| SCHEMBL32688412 | 0.76 | HSD17B10 (0.69) | NPC1PKMALDH1A1MAPTMAPK1 | |
| SCHEMBL13702429 | 0.76 | MAPT (0.57) | NPC1ALDH1A1MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | PLOD2 1971/4885PLOD3 1667/4885PLOD1 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.