Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.53 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.53 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688293 | 0.91 | PLOD2 (0.65) | PLOD2PLOD3PLOD1TSHRALDH1A1 | |
| SCHEMBL32688378 | 0.91 | ALDH1A1 (0.55) | PLOD2PLOD3PLOD1TSHRALDH1A1 | |
| SCHEMBL32688300 | 0.90 | ALDH1A1 (0.54) | PLOD2PLOD3PLOD1TSHRALDH1A1 | |
| SCHEMBL32688024 | 0.89 | PLOD2 (0.50) | PLOD2PLOD3PLOD1TSHRALDH1A1 | |
| SCHEMBL32688003 | 0.84 | GPR119 (0.52) | PLOD2PLOD3PLOD1TSHRALDH1A1 | |
| SCHEMBL124577 | 0.79 | KMT2A (0.59) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL32688044 | 0.78 | MEN1 (0.61) | TSHRALDH1A1MAPTLMNAUSP2 | |
| SCHEMBL32688049 | 0.78 | ERCC5 (0.60) | ALDH1A1MAPTKMOKDM4EMEN1 | |
| SCHEMBL5869170 | 0.78 | LMNA (0.45) | PLOD2PLOD3PLOD1TSHRALDH1A1 | |
| SCHEMBL28692105 | 0.78 | PLOD2 (0.67) | PLOD2PLOD3PLOD1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | PLOD2 1971/4885PLOD3 1667/4885PLOD1 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.