Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.65 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.65 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688239 | 0.91 | PLOD2 (0.53) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL32688378 | 0.90 | ALDH1A1 (0.55) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL32688300 | 0.89 | ALDH1A1 (0.54) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL32688024 | 0.88 | PLOD2 (0.50) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL8698788 | 0.84 | PLOD2 (0.56) | PLOD2PLOD3PLOD1HDAC3HDAC8 | |
| SCHEMBL3651005 | 0.84 | HDAC3 (0.59) | HDAC3HDAC8ALDH1A1MAPTLMNA | |
| SCHEMBL32688003 | 0.83 | GPR119 (0.52) | PLOD2PLOD3PLOD1ALDH1A1MAPT | |
| SCHEMBL17420453 | 0.80 | AGXT (0.56) | PLOD2PLOD3PLOD1HTR2CHTR1B | |
| SCHEMBL3656425 | 0.79 | GAA (0.60) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL10739904 | 0.79 | PLOD2 (0.66) | PLOD2PLOD3PLOD1HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | PLOD2 1971/4885PLOD3 1667/4885PLOD1 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.