Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LDHB | P07195 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688478 | 0.85 | ALDH1A1 (0.41) | ACMSDPOLBMEN1KMT2ACXCR2 | |
| SCHEMBL32688271 | 0.83 | ALDH1A1 (0.42) | ACMSDPOLBMEN1KMT2ALMNA | |
| SCHEMBL32688374 | 0.82 | NPC1 (0.40) | ACMSDPOLBMEN1KMT2ACXCR2 | |
| SCHEMBL32688409 | 0.78 | ACMSD (0.49) | ACMSDPOLBMEN1KMT2ALMNA | |
| SCHEMBL32688238 | 0.77 | PTPN1 (0.39) | ACMSDMEN1KMT2AHSD11B1LMNA | |
| SCHEMBL32688221 | 0.76 | SIRT2 (0.46) | POLBMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL29272645 | 0.76 | BRD4 (0.70) | ACMSDPOLBMEN1KMT2ACXCR2 | |
| SCHEMBL29554992 | 0.76 | BRD4 (0.70) | ACMSDPOLBMEN1KMT2ACXCR2 | |
| SCHEMBL32688056 | 0.76 | MET (0.41) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL32688358 | 0.75 | PSMD14 (0.43) | POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | ACMSD 142/4885POLB 508/4885MEN1 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.