SCHEMBL32688373

SCHEMBL32688373

CCOC(=O)CSc1[nH]c(=O)nc(-c2ccccc2)c1C#N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 4/20 0.54
▸ TDP1 Q9NUW8 3/20 0.52
▸ THRB P10828 1/20 0.52
▸ ALDH1A1 P00352 13/20 0.50
▸ HPGD P15428 7/20 0.50
▸ KDM4E B2RXH2 5/20 0.50
▸ MEN1 O00255 4/20 0.50
▸ KMT2A Q03164 4/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ PKM P14618 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ MAPT P10636 4/20 0.49
▸ TSHR P16473 2/20 0.49
▸ HSD17B10 Q99714 2/20 0.49
▸ ABL1 P00519 1/20 0.49
▸ GAA P10253 1/20 0.49
▸ RIN1 Q13671 1/20 0.49
▸ POLB P06746 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ NPSR1 Q6W5P4 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688248 0.85 ALDH1A1 (0.55) RXFP1TDP1ALDH1A1HPGDKDM4E
SCHEMBL32688052 0.75 MEN1 (0.56) RXFP1ALDH1A1HPGDMEN1KMT2A
SCHEMBL32688032 0.73 MEN1 (0.74) MEN1KMT2ASMN1; SMN2LMNAPOLB
SCHEMBL32688017 0.73 ACMSD (0.56) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL32688120 0.73 ACMSD (0.72) MEN1KMT2APOLB
SCHEMBL32688366 0.71 ACMSD (0.47) RXFP1ALDH1A1HPGDMEN1KMT2A
SCHEMBL14385592 0.70 RXFP1 (1.00) RXFP1TDP1THRBALDH1A1HPGD
SCHEMBL21527259 0.69 PTGS2 (0.83) ALDH1A1HPGDMEN1KMT2AGAA
SCHEMBL6442015 0.68 ALDH1A1 (0.66) RXFP1ALDH1A1HPGDKDM4EMEN1
SCHEMBL15525518 0.68 KMT2A (0.77) RXFP1TDP1THRBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK RXFP1 2355/4885TDP1 1571/4885THRB 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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