Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268889 | 0.89 | MAPK8 (0.32) | — | |
| SCHEMBL3267982 | 0.88 | MEN1 (0.34) | TP53 | |
| SCHEMBL3268931 | 0.88 | TUBB4A (0.37) | ALDH1A1TDP1 | |
| SCHEMBL3268577 | 0.86 | KDR (0.39) | ALDH1A1HTTTDP1ICAM1SELE | |
| SCHEMBL3268326 | 0.85 | CCNC (0.33) | — | |
| SCHEMBL3269102 | 0.82 | PDPK1 (0.36) | HTT | |
| SCHEMBL3175728 | 0.81 | PTGS2 (0.41) | ALDH1A1HTTL3MBTL1TDP1ICAM1 | |
| SCHEMBL3269317 | 0.81 | MEN1 (0.36) | GSK3BADKICAM1SELE | |
| SCHEMBL3275434 | 0.80 | EDNRA (0.43) | ALDH1A1 | |
| SCHEMBL3269989 | 0.79 | KDR (0.39) | HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784409-B1 | SUBSTITUTED THIENOPYRROLE CARBOXYLIC ACID AMIDES, PYRROLOTHIAZOLE CARBOXYLIC ACID AMIDES, AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMA INC (US) | 2010-06-16 | — | — | EP | claimed |