Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269102 | 0.89 | PDPK1 (0.36) | MEN1KMT2APDPK1DHFRTYMS | |
| SCHEMBL3269983 | 0.88 | ALDH1A1 (0.34) | TP53 | |
| SCHEMBL3268931 | 0.88 | TUBB4A (0.37) | MEN1KMT2A | |
| SCHEMBL3268326 | 0.85 | CCNC (0.33) | DHFRTYMS | |
| SCHEMBL3269791 | 0.84 | PDPK1 (0.36) | KMT2APDPK1RHEB | |
| SCHEMBL3268889 | 0.82 | MAPK8 (0.32) | PDPK1 | |
| SCHEMBL3174896 | 0.81 | MAP2 (0.39) | PDPK1CHEK2 | |
| SCHEMBL3269989 | 0.79 | KDR (0.39) | MEN1KMT2ATP53TYMS | |
| SCHEMBL3269545 | 0.79 | TYMS (0.35) | MEN1KMT2ATYMS | |
| SCHEMBL3268577 | 0.79 | KDR (0.39) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784409-B1 | SUBSTITUTED THIENOPYRROLE CARBOXYLIC ACID AMIDES, PYRROLOTHIAZOLE CARBOXYLIC ACID AMIDES, AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMA INC (US) | 2010-06-16 | — | — | EP | claimed |