⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352773 | 0.78 | LMNA (0.40) | — | |
| SCHEMBL2352779 | 0.78 | LMNA (0.40) | — | |
| SCHEMBL10053351 | 0.77 | P2RX7 (0.32) | — | |
| SCHEMBL6374100 | 0.75 | RBP4 (0.34) | — | |
| SCHEMBL3272484 | 0.71 | TUBB4A (0.31) | — | |
| SCHEMBL3272492 | 0.71 | TUBB4A (0.31) | — | |
| SCHEMBL13401459 | 0.69 | APLNR (0.31) | — | |
| SCHEMBL3273230 | 0.69 | TUBB4A (0.30) | — | |
| SCHEMBL3279213 | 0.69 | TUBB4A (0.34) | — | |
| SCHEMBL3273238 | 0.69 | TUBB4A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691785-B2 | Pyridine-3-ketone compound; plant growth controllers | SYNGENTA CROP PROTECTION, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080274891-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-7378375-B1 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1574510-A1 | Substituted pyridine herbicides | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| EP-1114030-B1 | PYRIDINE KETONES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| US-6838564-B2 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2005-01-04 | — | — | US | disclosed |
| US-20040097729-A1 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. | 2004-05-20 | — | — | US | disclosed |
| EP-1286985-A1 | SUBSTITUTED PYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2003-03-05 | — | — | EP | disclosed |
| US-6498125-B2 | Pyridine ketones useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-12-24 | — | — | US | disclosed |
| US-20020016345-A1 | Pyridine ketones useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-02-07 | — | — | US | disclosed |
| WO-2001094339-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-12-13 | — | — | WO | disclosed |
| EP-1114030-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | Syngenta Participations AG (CH) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015615-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-03-23 | — | — | WO | disclosed |