Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719065 | 0.88 | SLC22A1 (0.33) | — | |
| Tetrylammonium SCHEMBL3813154 | 0.86 | TSHR (0.36) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL5622110 | 0.85 | TSHR (0.32) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| SCHEMBL15229857 | 0.84 | — | — | |
| Tetramethylammonium Ion SCHEMBL12469916 | 0.80 | — | — | |
| SCHEMBL3629370 | 0.79 | — | — | |
| SCHEMBL3630341 | 0.77 | FDPS (0.33) | — | |
| SCHEMBL15136602 | 0.77 | KDM4E (0.30) | KDM4E | |
| SCHEMBL15136323 | 0.77 | PGK1 (0.30) | — | |
| SCHEMBL12469732 | 0.77 | PGK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541488-B2 | Process for the preparation of mono- and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates | MERCK PATENT GMBH (DE) | 2009-06-02 | — | — | US | claimed |
| EP-1685095-B1 | METHOD FOR THE PRODUCTION OF ORGANIC SALTS CONTAINING BIS(PERFLUOROALKYL)PHOSPHINATE ANIONS | MERCK PATENT GMBH (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1495035-B1 | METHOD FOR THE PRODUCTION OF BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS AND THE SALTS THEREOF | MERCK PATENT GMBH (DE) | 2010-06-30 | — | — | EP | disclosed |
| US-7576242-B2 | N-Ethylpyridinium bis(pentafluoroethyl)phosphinate; reacting tris(perfluoroalkyl)phosphine oxide is reacted with an alcohol and an organic base; ionic liquids | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |
| US-7541488-B2 | Process for the preparation of mono- and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates | MERCK PATENT GMBH (DE) | 2009-06-02 | — | — | US | disclosed |
| EP-1685143-B1 | METHOD FOR THE PRODUCTION OF MONO(FLUOROALKYL)PHOSPHORANES, BIS(FLUOROALKYL)PHOSPHORANES, AND THE CORRESPONDING ACIDS AND PHOSPHATES | MERCK PATENT GMBH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-20070128515-A1 | Process for the preparation of organic salts containing bis(perfluoroalkyl) phosphinate anions | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070088176-A1 | Process for the preparation of mono-and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates | MERECK PATENT GMBH (DE) | 2007-04-19 | — | — | US | disclosed |
| US-7202379-B2 | Process for the preparation of bis(perfluoroalkyl)phosphinic acids and salts thereof | MERCK PATENT GMBH (DE) | 2007-04-10 | — | — | US | disclosed |
| EP-1685143-A1 | METHOD FOR THE PRODUCTION OF MONO(FLUOROALKYL)PHOSPHORANES, BIS(FLUOROALKYL)PHOSPHORANES, AND THE CORRESPONDING ACIDS AND PHOSPHATES | Merck Patent GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| EP-1685095-A1 | METHOD FOR THE PRODUCTION OF ORGANIC SALTS CONTAINING BIS(PERFLUOROALKYL)PHOSPHINATE ANIONS | MERCK PATENT GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20050256334-A1 | Process for the preparation of bis(perfluoroalkyl)phosphinic acids and salts thereof | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| WO-2005049628-A1 | METHOD FOR THE PRODUCTION OF MONO(FLUOROALKYL)PHOSPHORANES, BIS(FLUOROALKYL)PHOSPHORANES, AND THE CORRESPONDING ACIDS AND PHOSPHATES | MERCK PATENT GMBH (DE) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005049555-A1 | METHOD FOR THE PRODUCTION OF ORGANIC SALTS CONTAINING BIS(PERFLUOROALKYL)PHOSPHINATE ANIONS | MERCK PATENT GMBH (DE) | 2005-06-02 | — | — | WO | disclosed |
| EP-1495035-A1 | METHOD FOR THE PRODUCTION OF BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS AND THE SALTS THEREOF | MERCK PATENT GmbH (DE) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087110-A1 | METHOD FOR THE PRODUCTION OF BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS AND THE SALTS THEREOF | MERCK PATENT GMBH (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088176-A1 | Process for the preparation of mono-and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates | PPIP5K2, PHOSPHO1, PFKFB1 | TSHR 3391/4885NFKB1 2066/4885KCNA1 1162/4885 |
| US-20070128515-A1 | Process for the preparation of organic salts containing bis(perfluoroalkyl) phosphinate anions | PHOSPHO1, PFAS, PFKFB1 | TSHR 1438/4885NFKB1 2080/4885KCNA1 1753/4885 |
| US-20050256334-A1 | Process for the preparation of bis(perfluoroalkyl)phosphinic acids and salts thereof | PFAS, PFKFB1, PFKFB4 | TSHR 473/4885NFKB1 3419/4885KCNA1 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.