SCHEMBL3271344

SCHEMBL3271344

CCCCC(C)(Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
MMP1 P03956 1/20 0.45
MMP9 P14780 1/20 0.45
MMP13 P45452 1/20 0.45
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
PPARD Q03181 1/20 0.44
CTSK P43235 1/20 0.42
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ARG1 P05089 1/20 0.41
ARG2 P78540 1/20 0.41
MMP8 P22894 1/20 0.41
EPHX2 P34913 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3271547 0.93 MMP1 (0.49) SMN1; SMN2HIF1AMMP1MMP9MMP13
SCHEMBL19182977 0.92 PPARG (0.46) SMN1; SMN2HIF1AMMP1MMP9MMP13
SCHEMBL3159710 0.89 SMN1; SMN2 (0.48) SMN1; SMN2HIF1AMMP1MMP9MMP13
SCHEMBL28755706 0.88 PPARA (0.49) SMN1; SMN2HIF1AMMP1MMP9MMP13
SCHEMBL28106001 0.87 BLM (0.54) HIF1APPARGPPARAPPARDSLC6A2
SCHEMBL20715652 0.87 PPARG (0.48) MMP1MMP9MMP13PPARGPPARA
SCHEMBL19182947 0.87 PPARG (0.48) MMP1MMP9MMP13PPARGPPARA
SCHEMBL28206355 0.85 MMP8 (0.48) MMP1MMP9MMP13CTSKMMP8
SCHEMBL25046029 0.84 ALDH1A1 (0.53) EPHX2ALDH1A1CYP3A4CYP2C19KMT2A
SCHEMBL6875021 0.83 MAPT (0.50) SMN1; SMN2HIF1APPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2819637-B1 FIXING OF PERFUME ON WET SKIN BEIERSDORF AG (DE) 2017-08-23 EP claimed
EP-0204736-B1 PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES L. GIVAUDAN & CIE Société Anonyme (CH) 1989-07-26 EP claimed
EP-0204736-A1 PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES. GIVAUDAN & CIE SA (CH) 1986-12-17 EP claimed
WO-1986003486-A1 PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES L. GIVAUDAN & CIE SOCIÉTÉ ANONYME (CH) 1986-06-19 WO claimed
US-11254647-B2 Benzo-fused heterocyclic derivatives useful as agonists of GPR120 JANSSEN PHARMACEUTICA NV (BE) 2022-02-22 US disclosed
US-20200317629-A1 BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120 JANSSEN PHARMACEUTICA NV (BE) 2020-10-08 US disclosed
US-10730847-B2 Benzo-fused heterocyclic derivatives useful as agonists of GPR120 JANSSEN PHARMACEUTICA NV (BE) 2020-08-04 US disclosed
US-20190152937-A1 BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120 JANSSEN PHARMACEUTICA NV (BE) 2019-05-23 US disclosed
EP-1920042-B1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCED PROPERTIES HENKEL AG & CO KGAA (DE) 2010-06-23 EP disclosed
EP-1920042-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCED PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-14 EP disclosed
WO-2007118747-A1 AQUEOUS CLEANING AGENT CONTAINING PERFUME HENKEL AG & CO. KGAA (DE) 2007-10-25 WO disclosed
WO-2007028480-A1 PARTICLES CONTAINING ZEOLITE AND PERFUME HAVING IMPROVED FRAGRANCE PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
WO-2007028478-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCED PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
EP-0204736-B1 PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES L. GIVAUDAN & CIE Société Anonyme (CH) 1989-07-26 EP disclosed
EP-0204736-A1 PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES. GIVAUDAN & CIE SA (CH) 1986-12-17 EP disclosed
WO-1986003486-A1 PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES L. GIVAUDAN & CIE SOCIÉTÉ ANONYME (CH) 1986-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317629-A1 BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120 GPR119, GPR180, GPR55 SMN1; SMN2 4174/4885HIF1A 1517/4885MMP1 4883/4885
US-20190152937-A1 BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120 GPR119, GPR180, GPR55 SMN1; SMN2 4174/4885HIF1A 1517/4885MMP1 4883/4885
US-11254647-B2 Benzo-fused heterocyclic derivatives useful as agonists of GPR120 GPR119, GPR180, GPR55 SMN1; SMN2 4174/4885HIF1A 1517/4885MMP1 4883/4885
US-10730847-B2 Benzo-fused heterocyclic derivatives useful as agonists of GPR120 GPR119, GPR180, GPR55 SMN1; SMN2 4174/4885HIF1A 1517/4885MMP1 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.